Matches in SemOpenAlex for { <https://semopenalex.org/work/W2332631432> ?p ?o ?g. }
- W2332631432 abstract "A group of patients with ischemic heart disease and myocardial infarction (N = 156) and a reference population sample (N = 300) were genotyped for 58 single nucleotide polymorphisms (SNPs) in the genes involved in extracellular matrix function and collagen metabolism or associated with cardiovascular diseases and atherosclerotic plaque stability. Genotyping was performed by mass-spectrometry with two multiplex sets of 27 and 31 SNPs. The study revealed different genetic composition of predisposition to cardiovascular disease continuum (CVDC) syntropy (patients with concomitant conditions: hypercholesterolemia, hypertension, and type-II diabetes mellitus, N = 96) and to isolated myocardial infarction (without these conditions, N = 60). Only the KIAA1462 gene (rs3739998) showed associations with both CVDC syntropy (OR = 1.71; 95% CI 1.19-2.45; р = 0.003) and isolated infarction (OR = 1.58; 95% CI 1.05-2.40; р = 0.028). Isolated myocardial infarction was also associated with LIG1 (rs20579) (OR = 2.08; 95% CI 1.06-4.17; р = 0.028) and ADAMDEC1 (rs3765124) (OR = 1.63; 95% CI 1.07-2.50; р = 0.020). CVDC syntropy was associated with CDKN2BAS1 (rs1333049) (OR = 1.48; 95% CI 1.03-2.12; р = 0.029) and APOA2 (rs5082) (OR = 1.47; 95% CI 1.02-2.11; р = 0.035). So, genes involved in fibrogenesis contribute to predisposition to the myocardial infarction as well. Isolated myocardial infarction and CVDC syntropy can be considered as pathogenetically different cardiovascular conditions, with different genes that contribute to the susceptibility." @default.
- W2332631432 created "2016-06-24" @default.
- W2332631432 creator A5011925076 @default.
- W2332631432 creator A5044907129 @default.
- W2332631432 creator A5055623764 @default.
- W2332631432 creator A5061199663 @default.
- W2332631432 creator A5061669036 @default.
- W2332631432 creator A5062880918 @default.
- W2332631432 creator A5070455148 @default.
- W2332631432 date "2016-01-01" @default.
- W2332631432 modified "2023-09-25" @default.
- W2332631432 title "Гены фиброгенеза в детерминации предрасположенности к инфаркту миокарда" @default.
- W2332631432 cites W1893413717 @default.
- W2332631432 cites W1971817750 @default.
- W2332631432 cites W1979091329 @default.
- W2332631432 cites W1984878259 @default.
- W2332631432 cites W1989982186 @default.
- W2332631432 cites W1993517485 @default.
- W2332631432 cites W2003753774 @default.
- W2332631432 cites W2004356910 @default.
- W2332631432 cites W2004475371 @default.
- W2332631432 cites W2006026018 @default.
- W2332631432 cites W2008920098 @default.
- W2332631432 cites W2009174760 @default.
- W2332631432 cites W2017667973 @default.
- W2332631432 cites W2020860086 @default.
- W2332631432 cites W2022976639 @default.
- W2332631432 cites W2025763679 @default.
- W2332631432 cites W2036198235 @default.
- W2332631432 cites W2039408641 @default.
- W2332631432 cites W2052780720 @default.
- W2332631432 cites W2053682284 @default.
- W2332631432 cites W2058021232 @default.
- W2332631432 cites W2061874270 @default.
- W2332631432 cites W2063405011 @default.
- W2332631432 cites W2071628128 @default.
- W2332631432 cites W2076983043 @default.
- W2332631432 cites W2078238387 @default.
- W2332631432 cites W2084449551 @default.
- W2332631432 cites W2085601951 @default.
- W2332631432 cites W2097279828 @default.
- W2332631432 cites W2100441646 @default.
- W2332631432 cites W2101214961 @default.
- W2332631432 cites W2113112852 @default.
- W2332631432 cites W2113495231 @default.
- W2332631432 cites W2116514399 @default.
- W2332631432 cites W2117490671 @default.
- W2332631432 cites W2120451046 @default.
- W2332631432 cites W2121772485 @default.
- W2332631432 cites W2130188373 @default.
- W2332631432 cites W2132388941 @default.
- W2332631432 cites W2134772956 @default.
- W2332631432 cites W2143353478 @default.
- W2332631432 cites W2145467303 @default.
- W2332631432 cites W2146870450 @default.
- W2332631432 cites W2147916449 @default.
- W2332631432 cites W2156954568 @default.
- W2332631432 cites W2158077895 @default.
- W2332631432 cites W2161395056 @default.
- W2332631432 cites W2168030915 @default.
- W2332631432 cites W2171945917 @default.
- W2332631432 cites W2278820887 @default.
- W2332631432 cites W2414287974 @default.
- W2332631432 cites W2420674115 @default.
- W2332631432 cites W2422766945 @default.
- W2332631432 cites W2804007336 @default.
- W2332631432 cites W36880162 @default.
- W2332631432 doi "https://doi.org/10.7868/s0026898415060099" @default.
- W2332631432 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27028815" @default.
- W2332631432 hasPublicationYear "2016" @default.
- W2332631432 type Work @default.
- W2332631432 sameAs 2332631432 @default.
- W2332631432 citedByCount "4" @default.
- W2332631432 countsByYear W23326314322019 @default.
- W2332631432 countsByYear W23326314322020 @default.
- W2332631432 countsByYear W23326314322023 @default.
- W2332631432 crossrefType "journal-article" @default.
- W2332631432 hasAuthorship W2332631432A5011925076 @default.
- W2332631432 hasAuthorship W2332631432A5044907129 @default.
- W2332631432 hasAuthorship W2332631432A5055623764 @default.
- W2332631432 hasAuthorship W2332631432A5061199663 @default.
- W2332631432 hasAuthorship W2332631432A5061669036 @default.
- W2332631432 hasAuthorship W2332631432A5062880918 @default.
- W2332631432 hasAuthorship W2332631432A5070455148 @default.
- W2332631432 hasConcept C104317684 @default.
- W2332631432 hasConcept C126322002 @default.
- W2332631432 hasConcept C134018914 @default.
- W2332631432 hasConcept C135763542 @default.
- W2332631432 hasConcept C153209595 @default.
- W2332631432 hasConcept C164705383 @default.
- W2332631432 hasConcept C2779134260 @default.
- W2332631432 hasConcept C2908647359 @default.
- W2332631432 hasConcept C500558357 @default.
- W2332631432 hasConcept C54355233 @default.
- W2332631432 hasConcept C555293320 @default.
- W2332631432 hasConcept C67636389 @default.
- W2332631432 hasConcept C71924100 @default.
- W2332631432 hasConcept C86803240 @default.
- W2332631432 hasConcept C99454951 @default.
- W2332631432 hasConceptScore W2332631432C104317684 @default.