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• W2332655488 abstract "Event Abstract Back to Event The rat SCO responsiveness to prolonged water deprivation: Implication of Reissner’s fiber and serotonin system Hicham CHATOUI1*, Omar El Hiba1, Abdeljalil Elgot1 and Halima GAMRANI1 1 Faculty of Science Semlalia, Cadi Ayyad University, Neuroscience Laboratory, Morocco The osmotic stress is a potent stimulus that can trigger several peripheral as well as central impairments. The brain is a vulnerable target of the osmotic stress and particularly circumventricular organs (CVOs) regarding their strategic localization as sensory organs of biochemical changes in the blood and cerebrospinal fluid circulations. The subcommissural organ (SCO) is a CVO which releases doubly in the CSF and blood circulation a glycoprotein called Reissner’s fiber (RF) that has been associated to several functions including electrolyte and water balances. The present work was aimed on the assessment of the secretory activity of the SCO and its serotoninergic innervation following 2 weeks of total water restriction in Wistar rat. Using the immunohistochemistry of RF and serotonin (5HT), our data showed a significant overall reduction of RF immunoreactivity within both ependymal and hypendymal cells of the SCO of dehydrated rats compared to their corresponding controls, this decrease was concomitant with an enhancement of fibers 5HT immunoreactivity in the SCO as well as in the classical ependyma and in the dorsal raphe nucleus (DRN), constituting the origin of this innervation. The present findings support the possible involvement of the SCO in the response to prolonged water deprivation by decreasing its secretory materials which may result from either a direct peripheral hormonal control and/or the consequence of the enhanced 5HT innervation of the SCO. Acknowledgements This work has been supported by the Moroccan CNRST (SC. Vie 05/10), le Centre national d’e´ tudes et de recherches sur le Sahara (CNERS); OTAN (PDD [CP] - [LST.CLG979823]). Keywords: rat, Dehydration, Serotonin (5HT), Reissner’s fiber (RF), Immunohistochemistry. Conference: 4th Conference of the Mediterrarnean Neuroscience Society, Istanbul, Türkiye, 30 Sep - 3 Oct, 2012. Presentation Type: Poster Presentation Topic: Abstracts Citation: CHATOUI H, El Hiba O, Elgot A and GAMRANI H (2013). The rat SCO responsiveness to prolonged water deprivation: Implication of Reissner’s fiber and serotonin system. Conference Abstract: 4th Conference of the Mediterrarnean Neuroscience Society. doi: 10.3389/conf.fnhum.2013.210.00015 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 28 Mar 2013; Published Online: 11 Apr 2013. * Correspondence: Dr. Hicham CHATOUI, Faculty of Science Semlalia, Cadi Ayyad University, Neuroscience Laboratory, Marrakesh, 40000, Morocco, Chatouih@yahoo.fr Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Hicham CHATOUI Omar El Hiba Abdeljalil Elgot Halima GAMRANI Google Hicham CHATOUI Omar El Hiba Abdeljalil Elgot Halima GAMRANI Google Scholar Hicham CHATOUI Omar El Hiba Abdeljalil Elgot Halima GAMRANI PubMed Hicham CHATOUI Omar El Hiba Abdeljalil Elgot Halima GAMRANI Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W2332655488 title "The rat SCO responsiveness to prolonged water deprivation: Implication of Reissner�s fiber and serotonin system" @default.
• W2332655488 doi "https://doi.org/10.3389/conf.fnhum.2013.210.00015" @default.
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