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- W2332655596 abstract "Rheumatoid arthritis (RA) is a chronic multisystem disease with an unknown etiology affecting about 1% of the world's population. Anemia is a frequently occurring extra articular manifestation of RA, being mostly of the normochromic & normocytic type. The aim of our study to assess and affirm whether the increased oxidative stress in inflamed joints is reflected by lipid-peroxidation? Also to check the alteration in levels of non -enzymatic antioxidant (vitamin E & vitamin C) in RA with Anemia. 100 patients with RA and 100 healthy individual were included in this study. A level of malonaldehyde (MDA), a lipid -peroxidation marker was measured by Utley's method. Non enzymatic antioxidant vitamin E and vitamin C was assayed in plasma/ serum by Shami Hashim & Carl A Burtis method. The levels of MDA were significantly increased (P<0.001) in RA as compared to control. Whereas levels of non-enzymatic antioxidant (Vitamin E & Vitamin C) were decreased in patients as compared to control. It is statistically significant (P<0.001). There was a raised oxidative stress and decreased non-enzymatic antioxidant (Vitamin E & Vitamin C) in anemic rheumatoid arthritis patients. These changes are probably due to efforts for reducing lipid-peroxidation and hence to lower tissue damage. 19 method .Lipid-peroxidation was determined by Utley's method 20 with the help of red cell hemolysate." @default.
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- W2332655596 date "2014-01-01" @default.
- W2332655596 modified "2023-10-16" @default.
- W2332655596 title "Lipid –peroxidation & Non-enzymatic antioxidant (Vitamin E & Vitamin C) serum levels in Anemic Rheumatoid arthritis patients" @default.
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- W2332655596 doi "https://doi.org/10.9790/3008-09110103" @default.
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