Matches in SemOpenAlex for { <https://semopenalex.org/work/W2332920003> ?p ?o ?g. }
- W2332920003 endingPage "84" @default.
- W2332920003 startingPage "78" @default.
- W2332920003 abstract "Lynch syndrome, also known as hereditary nonpolyposis colon cancer, is an autosomal dominant inherited cancer susceptibility syndrome characterized by germline mutations in mismatch repair genes such as MSH2, MSH6, PMS2, and MLH1. Although Lynch syndrome is most commonly associated with colon cancer, recent attention has shifted to its relationship to endometrial carcinoma. In women with Lynch syndrome, endometrial carcinoma is often the first clinical manifestation, alerting clinicians to the risk of subsequent Lynch syndrome–related cancers and the initiation of early screening and preventive strategies, which can significantly reduce cancer-related morbidity and mortality. Using traditional factors such as age and family history to decide which patients receive testing misses up to 70% of Lynch syndrome cases. The pathologist plays a vital role not only in identifying cases suggestive of Lynch syndrome, but also in interpreting screening tests. This review discusses the genetics and clinicopathologic features of Lynch syndrome–related endometrial carcinoma, as well as the screening protocols and preventive strategies used in the evaluation of patients who may be at risk for Lynch syndrome." @default.
- W2332920003 created "2016-06-24" @default.
- W2332920003 creator A5076326409 @default.
- W2332920003 creator A5089159861 @default.
- W2332920003 date "2014-01-01" @default.
- W2332920003 modified "2023-10-18" @default.
- W2332920003 title "Lynch Syndrome in Endometrial Carcinoma" @default.
- W2332920003 cites W1893792948 @default.
- W2332920003 cites W1903698419 @default.
- W2332920003 cites W1969637146 @default.
- W2332920003 cites W1970415574 @default.
- W2332920003 cites W1984037401 @default.
- W2332920003 cites W2007161712 @default.
- W2332920003 cites W2011575493 @default.
- W2332920003 cites W2013272885 @default.
- W2332920003 cites W2019940629 @default.
- W2332920003 cites W2022667011 @default.
- W2332920003 cites W2036649093 @default.
- W2332920003 cites W2037342915 @default.
- W2332920003 cites W2037395897 @default.
- W2332920003 cites W2041758733 @default.
- W2332920003 cites W2042111215 @default.
- W2332920003 cites W2068400231 @default.
- W2332920003 cites W2068939856 @default.
- W2332920003 cites W2073988279 @default.
- W2332920003 cites W2083421227 @default.
- W2332920003 cites W2095767966 @default.
- W2332920003 cites W2099162862 @default.
- W2332920003 cites W2103645868 @default.
- W2332920003 cites W2112677111 @default.
- W2332920003 cites W2122079027 @default.
- W2332920003 cites W2124561249 @default.
- W2332920003 cites W2124896165 @default.
- W2332920003 cites W2128793721 @default.
- W2332920003 cites W2135116174 @default.
- W2332920003 cites W2137098494 @default.
- W2332920003 cites W2137257426 @default.
- W2332920003 cites W2137304051 @default.
- W2332920003 cites W2141462854 @default.
- W2332920003 cites W2141930394 @default.
- W2332920003 cites W2143895061 @default.
- W2332920003 cites W2146263344 @default.
- W2332920003 cites W2156243614 @default.
- W2332920003 cites W2156299764 @default.
- W2332920003 cites W2159032347 @default.
- W2332920003 cites W2159899668 @default.
- W2332920003 cites W2163958652 @default.
- W2332920003 cites W2315998729 @default.
- W2332920003 cites W3023234498 @default.
- W2332920003 cites W4244110111 @default.
- W2332920003 doi "https://doi.org/10.1097/pcr.0000000000000022" @default.
- W2332920003 hasPublicationYear "2014" @default.
- W2332920003 type Work @default.
- W2332920003 sameAs 2332920003 @default.
- W2332920003 citedByCount "3" @default.
- W2332920003 countsByYear W23329200032017 @default.
- W2332920003 countsByYear W23329200032019 @default.
- W2332920003 countsByYear W23329200032021 @default.
- W2332920003 crossrefType "journal-article" @default.
- W2332920003 hasAuthorship W2332920003A5076326409 @default.
- W2332920003 hasAuthorship W2332920003A5089159861 @default.
- W2332920003 hasConcept C104317684 @default.
- W2332920003 hasConcept C111425858 @default.
- W2332920003 hasConcept C121608353 @default.
- W2332920003 hasConcept C126322002 @default.
- W2332920003 hasConcept C13514818 @default.
- W2332920003 hasConcept C143998085 @default.
- W2332920003 hasConcept C2776559941 @default.
- W2332920003 hasConcept C2776674815 @default.
- W2332920003 hasConcept C2777088508 @default.
- W2332920003 hasConcept C2777277851 @default.
- W2332920003 hasConcept C2777546739 @default.
- W2332920003 hasConcept C2778677574 @default.
- W2332920003 hasConcept C2779115348 @default.
- W2332920003 hasConcept C2780673598 @default.
- W2332920003 hasConcept C29456083 @default.
- W2332920003 hasConcept C501734568 @default.
- W2332920003 hasConcept C526805850 @default.
- W2332920003 hasConcept C54355233 @default.
- W2332920003 hasConcept C60748783 @default.
- W2332920003 hasConcept C71924100 @default.
- W2332920003 hasConcept C86803240 @default.
- W2332920003 hasConceptScore W2332920003C104317684 @default.
- W2332920003 hasConceptScore W2332920003C111425858 @default.
- W2332920003 hasConceptScore W2332920003C121608353 @default.
- W2332920003 hasConceptScore W2332920003C126322002 @default.
- W2332920003 hasConceptScore W2332920003C13514818 @default.
- W2332920003 hasConceptScore W2332920003C143998085 @default.
- W2332920003 hasConceptScore W2332920003C2776559941 @default.
- W2332920003 hasConceptScore W2332920003C2776674815 @default.
- W2332920003 hasConceptScore W2332920003C2777088508 @default.
- W2332920003 hasConceptScore W2332920003C2777277851 @default.
- W2332920003 hasConceptScore W2332920003C2777546739 @default.
- W2332920003 hasConceptScore W2332920003C2778677574 @default.
- W2332920003 hasConceptScore W2332920003C2779115348 @default.
- W2332920003 hasConceptScore W2332920003C2780673598 @default.
- W2332920003 hasConceptScore W2332920003C29456083 @default.
- W2332920003 hasConceptScore W2332920003C501734568 @default.