FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2332968100> ?p ?o ?g. }

• W2332968100 endingPage "112" @default.
• W2332968100 startingPage "82" @default.
• W2332968100 abstract "This review gives an update of the current scientific evidence on the efficacy of the adjunctive use of systemic and local antibiotics/antimicrobials in the treatment of periodontitis. In particular, it addresses whether their use can improve the results of nonsurgical mechanical therapy in mild-to-moderate forms of the disease. Large numbers of randomized clinical trials and systematic reviews with meta-analyses have clearly established that adjunctive systemic antibiotics, combined with mechanical debridement, offer clinical improvements additional to those obtained with scaling and root planing alone. These effects are more pronounced in aggressive periodontitis and in initially deep pockets, whereas more limited additional improvements, of 0.3 mm for additional pocket reduction and 0.2 mm for additional clinical attachment gain, have been documented for moderately deep sites (4–6 mm) in patients with chronic periodontitis. The marginal clinical benefit in patients with moderate disease has to be balanced against possible side effects. Notably, it has to be realized that an increasing number of warnings have been articulated against the unrestricted use of antibiotics in treating periodontal diseases because of the emerging global public health issue of bacterial resistance. The effects of the adjunctive local administration of antimicrobials have also been very well documented in several systematic reviews. Overall, in persistent or recurrent localized deep sites, the application of antimicrobials by sustained-delivery devices may offer a benefit of an additional 0.4 mm in pocket depth reduction and 0.3 mm in clinical attachment level gain. In conclusion, the slight additional benefits of adjunctive antimicrobials, which were shown for moderate forms of periodontitis, have to be balanced against their side effects and therefore their prescription should be limited as much as possible." @default.
• W2332968100 created "2016-06-24" @default.
• W2332968100 creator A5063557940 @default.
• W2332968100 creator A5066563878 @default.
• W2332968100 date "2016-04-04" @default.
• W2332968100 modified "2023-10-16" @default.
• W2332968100 title "Antibiotics/antimicrobials: systemic and local administration in the therapy of mild to moderately advanced periodontitis" @default.
• W2332968100 cites W126262189 @default.
• W2332968100 cites W1479763822 @default.
• W2332968100 cites W1534626330 @default.
• W2332968100 cites W1557749508 @default.
• W2332968100 cites W1572591850 @default.
• W2332968100 cites W1602879250 @default.
• W2332968100 cites W1753123953 @default.
• W2332968100 cites W1753159784 @default.
• W2332968100 cites W1787348899 @default.
• W2332968100 cites W1825642470 @default.
• W2332968100 cites W1849733024 @default.
• W2332968100 cites W1858894787 @default.
• W2332968100 cites W1885633068 @default.
• W2332968100 cites W1897611316 @default.
• W2332968100 cites W1924976039 @default.
• W2332968100 cites W1926431033 @default.
• W2332968100 cites W1937184610 @default.
• W2332968100 cites W1948857334 @default.
• W2332968100 cites W1959624831 @default.
• W2332968100 cites W1966921473 @default.
• W2332968100 cites W1967246447 @default.
• W2332968100 cites W1967848728 @default.
• W2332968100 cites W1970179763 @default.
• W2332968100 cites W1971072534 @default.
• W2332968100 cites W1975675040 @default.
• W2332968100 cites W1976327936 @default.
• W2332968100 cites W1977072452 @default.
• W2332968100 cites W1977373426 @default.
• W2332968100 cites W1980551152 @default.
• W2332968100 cites W1981275172 @default.
• W2332968100 cites W1981733915 @default.
• W2332968100 cites W1982594769 @default.
• W2332968100 cites W1982762170 @default.
• W2332968100 cites W1983016083 @default.
• W2332968100 cites W1984320817 @default.
• W2332968100 cites W1986460338 @default.
• W2332968100 cites W1988416860 @default.
• W2332968100 cites W1989169030 @default.
• W2332968100 cites W1989939902 @default.
• W2332968100 cites W1990960804 @default.
• W2332968100 cites W1994482779 @default.
• W2332968100 cites W1994526435 @default.
• W2332968100 cites W1996009278 @default.
• W2332968100 cites W1999071869 @default.
• W2332968100 cites W2001181093 @default.
• W2332968100 cites W2003647170 @default.
• W2332968100 cites W2007159007 @default.
• W2332968100 cites W2007669655 @default.
• W2332968100 cites W2008463164 @default.
• W2332968100 cites W2008504684 @default.
• W2332968100 cites W2008942033 @default.
• W2332968100 cites W2009034402 @default.
• W2332968100 cites W2012251902 @default.
• W2332968100 cites W2012977051 @default.
• W2332968100 cites W2013329897 @default.
• W2332968100 cites W2014676683 @default.
• W2332968100 cites W2016513616 @default.
• W2332968100 cites W2017304020 @default.
• W2332968100 cites W2017328348 @default.
• W2332968100 cites W2018380674 @default.
• W2332968100 cites W2018540964 @default.
• W2332968100 cites W2021590962 @default.
• W2332968100 cites W2021838232 @default.
• W2332968100 cites W2024217238 @default.
• W2332968100 cites W2026086908 @default.
• W2332968100 cites W2029374202 @default.
• W2332968100 cites W2029594785 @default.
• W2332968100 cites W2033002674 @default.
• W2332968100 cites W2035263644 @default.
• W2332968100 cites W2039832774 @default.
• W2332968100 cites W2040357628 @default.
• W2332968100 cites W2041168082 @default.
• W2332968100 cites W2043442946 @default.
• W2332968100 cites W2044230237 @default.
• W2332968100 cites W2045812506 @default.
• W2332968100 cites W2045905510 @default.
• W2332968100 cites W2047066801 @default.
• W2332968100 cites W2047181164 @default.
• W2332968100 cites W2047391119 @default.
• W2332968100 cites W2048201917 @default.
• W2332968100 cites W2050035976 @default.
• W2332968100 cites W2052233772 @default.
• W2332968100 cites W2053330602 @default.
• W2332968100 cites W2053539448 @default.
• W2332968100 cites W2053813337 @default.
• W2332968100 cites W2056857562 @default.
• W2332968100 cites W2057527201 @default.
• W2332968100 cites W2059400368 @default.
• W2332968100 cites W2060024150 @default.
• W2332968100 cites W2061384794 @default.
• W2332968100 cites W2061411813 @default.

• next