Matches in SemOpenAlex for { <https://semopenalex.org/work/W2333014775> ?p ?o ?g. }
- W2333014775 endingPage "e2075" @default.
- W2333014775 startingPage "e2075" @default.
- W2333014775 abstract "The aim of the study was to investigate the safety and efficacy of using MLT in the treatment of open-angle glaucoma (OAG). This prospective cohort included subjects ≥18 years of age with OAG, defined as the open angle on gonioscopy with glaucomatous optic neuropathy evident from optical coherence tomography. Subjects with IOP < 21 mm Hg were classified as normal tension glaucoma and those with IOP ≥21 mm Hg were classified as primary open-angle glaucoma. Those with angle closure, secondary glaucoma, prior laser trabeculoplasty, use of systemic IOP-lowering medications, corneal pathologies, follow-up <6 months, recent intraocular surgery, or only 1 functional eye were excluded. A single session of unilateral MLT treatment was delivered using a 577 nm diode laser to 360° of the trabecular meshwork to reduce IOP or medication load. Medications were titrated up or down at 1 month after laser to achieve a 25% IOP reduction from presentation or an IOP <18 mm Hg, whichever was lower. The following were compared using the Repeated Measures ANOVA with Bonferroni's Multiple Comparison Test: IOP (on presentation, pre-MLT, day 1, 1 week, 1 month, 3 months, and 6 months after MLT) and the number of medications (pre-MLT, 3 months, and 6 months after MLT). After 6 months, responders with initial success to MLT (IOP reduction ≥20% at 1 month) received treatment in the fellow eye. In 48 subjects with OAG, the mean number of MLT shots applied was 120.5 ± 2.0 shots using a mean energy of 1000 mW per shot. Only 7.5% had a mild, self-limiting anterior uveitis postlaser with no change in the Snellen visual acuity at 6 months (P's > 0.5). The IOP and number of medications were significantly reduced at all time intervals following MLT compared to the pre-MLT level (P's < 0.0001). At 6 months, the IOP was reduced by 19.5% in addition to a 21.4% reduction in medication compared to pretreatment levels. The MLT success rate was 72.9%. During the first 6 months only 2.1% required a repeated laser trabeculoplasty. MLT was effective in reducing IOP and medications in OAG with minimal postlaser inflammation and low failure rate at 6 months following laser." @default.
- W2333014775 created "2016-06-24" @default.
- W2333014775 creator A5020653718 @default.
- W2333014775 creator A5053812047 @default.
- W2333014775 creator A5066524278 @default.
- W2333014775 creator A5088487522 @default.
- W2333014775 date "2015-12-01" @default.
- W2333014775 modified "2023-10-01" @default.
- W2333014775 title "MicroPulse Laser Trabeculoplasty for the Treatment of Open-Angle Glaucoma" @default.
- W2333014775 cites W14047651 @default.
- W2333014775 cites W1564203607 @default.
- W2333014775 cites W1648769816 @default.
- W2333014775 cites W1714757802 @default.
- W2333014775 cites W1969281040 @default.
- W2333014775 cites W1970548437 @default.
- W2333014775 cites W1971678686 @default.
- W2333014775 cites W1979356019 @default.
- W2333014775 cites W1986468793 @default.
- W2333014775 cites W1991557880 @default.
- W2333014775 cites W1994514723 @default.
- W2333014775 cites W1999547419 @default.
- W2333014775 cites W2011629305 @default.
- W2333014775 cites W2018585024 @default.
- W2333014775 cites W2025920621 @default.
- W2333014775 cites W2031305939 @default.
- W2333014775 cites W2047480246 @default.
- W2333014775 cites W2058127365 @default.
- W2333014775 cites W2059858483 @default.
- W2333014775 cites W2071384510 @default.
- W2333014775 cites W2082054485 @default.
- W2333014775 cites W2086120098 @default.
- W2333014775 cites W2100156909 @default.
- W2333014775 cites W2110897487 @default.
- W2333014775 cites W2115360088 @default.
- W2333014775 cites W2127559507 @default.
- W2333014775 cites W2135006936 @default.
- W2333014775 cites W2148890166 @default.
- W2333014775 cites W2152239032 @default.
- W2333014775 cites W2319480263 @default.
- W2333014775 cites W2321377840 @default.
- W2333014775 cites W2410036917 @default.
- W2333014775 cites W4375816514 @default.
- W2333014775 cites W4376454112 @default.
- W2333014775 cites W623692186 @default.
- W2333014775 doi "https://doi.org/10.1097/md.0000000000002075" @default.
- W2333014775 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5008476" @default.
- W2333014775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26656331" @default.
- W2333014775 hasPublicationYear "2015" @default.
- W2333014775 type Work @default.
- W2333014775 sameAs 2333014775 @default.
- W2333014775 citedByCount "24" @default.
- W2333014775 countsByYear W23330147752016 @default.
- W2333014775 countsByYear W23330147752017 @default.
- W2333014775 countsByYear W23330147752018 @default.
- W2333014775 countsByYear W23330147752019 @default.
- W2333014775 countsByYear W23330147752021 @default.
- W2333014775 countsByYear W23330147752022 @default.
- W2333014775 countsByYear W23330147752023 @default.
- W2333014775 crossrefType "journal-article" @default.
- W2333014775 hasAuthorship W2333014775A5020653718 @default.
- W2333014775 hasAuthorship W2333014775A5053812047 @default.
- W2333014775 hasAuthorship W2333014775A5066524278 @default.
- W2333014775 hasAuthorship W2333014775A5088487522 @default.
- W2333014775 hasBestOaLocation W23330147751 @default.
- W2333014775 hasConcept C118487528 @default.
- W2333014775 hasConcept C141071460 @default.
- W2333014775 hasConcept C188816634 @default.
- W2333014775 hasConcept C2778527774 @default.
- W2333014775 hasConcept C2780179686 @default.
- W2333014775 hasConcept C2780892088 @default.
- W2333014775 hasConcept C2781092963 @default.
- W2333014775 hasConcept C2781121420 @default.
- W2333014775 hasConcept C2991803831 @default.
- W2333014775 hasConcept C71924100 @default.
- W2333014775 hasConceptScore W2333014775C118487528 @default.
- W2333014775 hasConceptScore W2333014775C141071460 @default.
- W2333014775 hasConceptScore W2333014775C188816634 @default.
- W2333014775 hasConceptScore W2333014775C2778527774 @default.
- W2333014775 hasConceptScore W2333014775C2780179686 @default.
- W2333014775 hasConceptScore W2333014775C2780892088 @default.
- W2333014775 hasConceptScore W2333014775C2781092963 @default.
- W2333014775 hasConceptScore W2333014775C2781121420 @default.
- W2333014775 hasConceptScore W2333014775C2991803831 @default.
- W2333014775 hasConceptScore W2333014775C71924100 @default.
- W2333014775 hasIssue "49" @default.
- W2333014775 hasLocation W23330147751 @default.
- W2333014775 hasLocation W23330147752 @default.
- W2333014775 hasLocation W23330147753 @default.
- W2333014775 hasLocation W23330147754 @default.
- W2333014775 hasOpenAccess W2333014775 @default.
- W2333014775 hasPrimaryLocation W23330147751 @default.
- W2333014775 hasRelatedWork W1975088893 @default.
- W2333014775 hasRelatedWork W2013915487 @default.
- W2333014775 hasRelatedWork W2026300329 @default.
- W2333014775 hasRelatedWork W2032704621 @default.
- W2333014775 hasRelatedWork W2060567963 @default.
- W2333014775 hasRelatedWork W2064676060 @default.
- W2333014775 hasRelatedWork W2085178917 @default.