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- W2333163401 endingPage "18263" @default.
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- W2333163401 abstract "We developed a hybrid technique combining optical tweezers and single-molecule three-color fluorescence resonance energy transfer (FRET). In demonstrative experiments, we observed the force-sensitive correlated motion of three helical arms of a Holliday junction and identified the independent unfolding/folding dynamics of two DNA hairpins of the same length. With 3 times the number of observable elements of single-molecule FRET, this new instrument will enable the measurement of the complex, multidimensional effects of mechanical forces in various biomolecular systems, such as RNA and proteins." @default.
- W2333163401 created "2016-06-24" @default.
- W2333163401 creator A5037358268 @default.
- W2333163401 creator A5067749153 @default.
- W2333163401 date "2013-11-26" @default.
- W2333163401 modified "2023-10-05" @default.
- W2333163401 title "An Optical Trap Combined with Three-Color FRET" @default.
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- W2333163401 doi "https://doi.org/10.1021/ja408767p" @default.
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