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- W2333169968 abstract "Recently we1 showed that the treatment of anti-Brucella horse serum with ketene for 35 min or more prevents anaphylactic shock in animals sensitized to the original antiserum. Furthermore, such a serum still retains the major part of its agglutinating antibody. The purpose of this paper is to record the influence of ketene on the protective power of antipneumococcus serum.Type I antipneumococcus horse serum, containing 200 units per cc (1642-1, Eli Lilly and Co.) was tested. To 10 cc of the serum to be ketenized, 0.6 g of NaHCO3 was added to buffer the acetic acid which is formed during the process. A drop of caprylic alcohol was introduced to prevent foaming. Ketene gas was passed through the serum for 35 min at the rate of 100 bubbles per min (diam of inlet tube, 4 mm). At the end of the ketenizing process the pH of the serum was 7.8. Both the ketene treated and the original antisera were diluted with 0.85% physiological salt solution until 1 unit was contained in 0.5 cc. In this test a constant amount ..." @default.
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- W2333169968 date "1938-06-01" @default.
- W2333169968 modified "2023-09-26" @default.
- W2333169968 title "Influence of Ketene on the Potency of Antipneumococcus Serum." @default.
- W2333169968 doi "https://doi.org/10.3181/00379727-38-10061" @default.
- W2333169968 hasPublicationYear "1938" @default.
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