FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2333228521> ?p ?o ?g. }

• W2333228521 endingPage "1229" @default.
• W2333228521 startingPage "1228.3" @default.
• W2333228521 abstract "<h3>Background</h3> Comorbidity in patients with Rheumatoid Arthritis (RA) is highly prevalent and plays an important role in determining RA related outcomes. Several studies have reported the negative association of comorbidity with functioning in general. The information about the association of specific comorbidities with functioning in patients with RA is limited. Evaluating specific comorbidities will provide valuable information for clinical practice and the management of patients with RA. <h3>Objectives</h3> To investigate the long term association of a wide range of specific comorbidities with physical and mental functioning in patients with RA. <h3>Methods</h3> Longitudinal data over a period of 11 years were collected from 882 patients with RA at study inclusion. Somatic comorbidity was measured at baseline, with a questionnaire including 20 chronic diseases, from which 9 categories of chronic somatic comorbidity were created. Comorbid depression was measured at baseline, with the Center for Epidemiologic Depression Scale. Physical functioning was measured with the Health Assessment Questionnaire (HAQ) and with the physical component scales of the Short Form 36 health survey (SF-36). Mental functioning was measured with the mental component scales of the SF-36. To determine the impact of specific comorbid conditions on functioning and on change in functioning we performed a longitudinal analysis. <h3>Results</h3> At baseline, 72% of the patients were women, their mean age ± SD was 59.3±14.8 years, their median disease duration was 5.0 years, and 68% had ≥1 comorbid condition. The mean HAQ score for an average patient was 0.98 on average over the 11-years follow-up period. Circulatory conditions (mean HAQ score +0.28) and depression (+0.38) were associated (p<.05) with low physical functioning according to the HAQ. An average patient with a circulatory condition had a mean HAQ score of 0.98 +0.28 =1.46. Circulatory (mean SF-36 score -3.23), respiratory (-2.74), musculoskeletal conditions (-2.85), cancer (-5.26) and depression (-3.36) were associated (p<.05) with low physical functioning according to the SF-36, while respiratory conditions (-2.28) and depression (-12.81) were associated (p<.05) with low mental functioning. The improvement in physical functioning according to the HAQ was 0.01 annually for an average patient. Genitourinary conditions were associated with a decline in physical functioning over time (p<.05). An average patient with a genitourinary condition declined in physical functioning with 0.01–0.04 = -0.03 annually. Digestive conditions were associated (p<0.05) with a decline in mental functioning. <h3>Conclusions</h3> Patients with specific comorbid conditions have an increased risk of low or declining functioning on the long term. Targeted attention for these specific comorbid conditions by clinicians and general practitioners is important. Diagnostics during the course of the disease, adequate referral to and working together with other specialists might improve physical and mental functioning in patients with RA. <h3>Disclosure of Interest</h3> None declared <h3>DOI</h3> 10.1136/annrheumdis-2014-eular.2909" @default.
• W2333228521 created "2016-06-24" @default.
• W2333228521 creator A5000576853 @default.
• W2333228521 creator A5024087229 @default.
• W2333228521 creator A5028215757 @default.
• W2333228521 creator A5032033010 @default.
• W2333228521 creator A5091166430 @default.
• W2333228521 creator A5091881332 @default.
• W2333228521 date "2014-06-01" @default.
• W2333228521 modified "2023-09-26" @default.
• W2333228521 title "AB1184-HPR Physical and Mental Functioning in Patients with Established Rheumatoid Arthritis over an 11-Year Follow-Up Period: the Role of Specific Comorbidities" @default.
• W2333228521 doi "https://doi.org/10.1136/annrheumdis-2014-eular.2909" @default.
• W2333228521 hasPublicationYear "2014" @default.
• W2333228521 type Work @default.
• W2333228521 sameAs 2333228521 @default.
• W2333228521 citedByCount "0" @default.
• W2333228521 crossrefType "journal-article" @default.
• W2333228521 hasAuthorship W2333228521A5000576853 @default.
• W2333228521 hasAuthorship W2333228521A5024087229 @default.
• W2333228521 hasAuthorship W2333228521A5028215757 @default.
• W2333228521 hasAuthorship W2333228521A5032033010 @default.
• W2333228521 hasAuthorship W2333228521A5091166430 @default.
• W2333228521 hasAuthorship W2333228521A5091881332 @default.
• W2333228521 hasConcept C118552586 @default.
• W2333228521 hasConcept C126322002 @default.
• W2333228521 hasConcept C134362201 @default.
• W2333228521 hasConcept C139719470 @default.
• W2333228521 hasConcept C142724271 @default.
• W2333228521 hasConcept C162324750 @default.
• W2333228521 hasConcept C1862650 @default.
• W2333228521 hasConcept C2776867660 @default.
• W2333228521 hasConcept C2777575956 @default.
• W2333228521 hasConcept C2777895361 @default.
• W2333228521 hasConcept C2779159551 @default.
• W2333228521 hasConcept C71924100 @default.
• W2333228521 hasConceptScore W2333228521C118552586 @default.
• W2333228521 hasConceptScore W2333228521C126322002 @default.
• W2333228521 hasConceptScore W2333228521C134362201 @default.
• W2333228521 hasConceptScore W2333228521C139719470 @default.
• W2333228521 hasConceptScore W2333228521C142724271 @default.
• W2333228521 hasConceptScore W2333228521C162324750 @default.
• W2333228521 hasConceptScore W2333228521C1862650 @default.
• W2333228521 hasConceptScore W2333228521C2776867660 @default.
• W2333228521 hasConceptScore W2333228521C2777575956 @default.
• W2333228521 hasConceptScore W2333228521C2777895361 @default.
• W2333228521 hasConceptScore W2333228521C2779159551 @default.
• W2333228521 hasConceptScore W2333228521C71924100 @default.
• W2333228521 hasIssue "Suppl 2" @default.
• W2333228521 hasLocation W23332285211 @default.
• W2333228521 hasOpenAccess W2333228521 @default.
• W2333228521 hasPrimaryLocation W23332285211 @default.
• W2333228521 hasRelatedWork W2009134158 @default.
• W2333228521 hasRelatedWork W2156283049 @default.
• W2333228521 hasRelatedWork W2316954211 @default.
• W2333228521 hasRelatedWork W2326094713 @default.
• W2333228521 hasRelatedWork W2427075784 @default.
• W2333228521 hasRelatedWork W2427452099 @default.
• W2333228521 hasRelatedWork W2761967325 @default.
• W2333228521 hasRelatedWork W4245782456 @default.
• W2333228521 hasRelatedWork W4301332622 @default.
• W2333228521 hasRelatedWork W4365452358 @default.
• W2333228521 hasVolume "73" @default.
• W2333228521 isParatext "false" @default.
• W2333228521 isRetracted "false" @default.
• W2333228521 magId "2333228521" @default.
• W2333228521 workType "article" @default.