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• W2333441010 abstract "Prostate cancer appears in two versions: familial and sporadic. In the development of sporadic prostate cancer, sequence variations in some genes, especially in genes involved in steroid hormone metabolism has been considered important. CYP19 gene is one of the most interesting. The product of this gene converts the C19 steroid to estrogen. Some studies have shown long allele of TTTA in intron4, as a tetra nucleotide repeat is associated with increased risk of prostate cancer.In this case/ control research we studied the association of TTTA repeat variations and prostate cancer risk among 59 patients with sporadic prostate cancer and 95 healthy men which were referred to Shohada-e -Tajrish Hospital, under SBMU license. This study did not revealed significant association between various length of tetra nucleotide repeats (including long and short repeats) and prostate cancer risk (with P-value=0.4). Results of our study do not support about considered role of TTTA repeat variations and prostate cancer in Iranian population." @default.
• W2333441010 created "2016-06-24" @default.
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• W2333441010 date "2014-01-01" @default.
• W2333441010 modified "2023-09-27" @default.
• W2333441010 title "No association between TTTA short tandem repeat (STR) of the CYP19 gene and prostate cancer risk in Iranian population: A case control study" @default.
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