Matches in SemOpenAlex for { <https://semopenalex.org/work/W2333466121> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2333466121 endingPage "1058" @default.
- W2333466121 startingPage "1051" @default.
- W2333466121 abstract "As a first step of investigating male predominance of bladder cancer incidence, we have studied relationships between rat bladder carcinogenesis, induced by BBN, and changes of pituitary-testicular axis, induced by a LH-RH analogue.The rats were divided into the following five groups. The first group (Age matched control group) was given normal drinking water for 30 weeks. The 2nd group (BBN group) was given a drinking water containing 0.05% BBN for 6 weeks. The 3rd group (LH-RH group) was given subcutaneous injections of a LH-RH analogue depot every four weeks. The 4th group (LH-RH+BBN group) was given subcutaneous injections of the LH-RH analogue depot every four weeks and a drinking water containing 0.05% BBN for 6 weeks. The 5th group (castration group) was castrated and given normal drinking water. The results were summarized as follows. 1) Serum LH, FSH and testosterone levels reached their peaks one day after the LH-RH analogue injection and decreased afterwards. Testosterone marked a castration level one week after the LH-RH analogue injection. 2) There was no significant difference between the BBN and non BBN groups in serum LH, FSH and testosterone levels. Thus, BBN did not influence the pitutary-testicular axis and the action of the LH-RH analogues. 3) Incidence of cancer was higher in the group of BBN+LH-RH than in the gorup of BBN 8 weeks after the start of the experiment. Then, the incidence was reversed between 20 weeks and 26 weeks; finally it became almost the same at 30 weeks. This phenomenon may be explained by the experimented schedule we applied; that is, BBN and LH-RH analogue were administered simultaneously. 4) Thus, changes of the pituitary-testicular axis induced by the LH-RH anlaoue seemed to have influence on blader carcinogen." @default.
- W2333466121 created "2016-06-24" @default.
- W2333466121 creator A5007477518 @default.
- W2333466121 creator A5039492144 @default.
- W2333466121 creator A5056993350 @default.
- W2333466121 creator A5059395063 @default.
- W2333466121 creator A5068203096 @default.
- W2333466121 date "1989-01-01" @default.
- W2333466121 modified "2023-09-26" @default.
- W2333466121 title "EFFECTS OF LH-RH ANALOGUE ON PITUITARY-TESTICULAR AXIS AND BLADDER CARCINOGENESIS OF BBN ADMINISTERED MALE RATS" @default.
- W2333466121 doi "https://doi.org/10.5980/jpnjurol1989.80.1051" @default.
- W2333466121 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2514311" @default.
- W2333466121 hasPublicationYear "1989" @default.
- W2333466121 type Work @default.
- W2333466121 sameAs 2333466121 @default.
- W2333466121 citedByCount "2" @default.
- W2333466121 countsByYear W23334661212015 @default.
- W2333466121 crossrefType "journal-article" @default.
- W2333466121 hasAuthorship W2333466121A5007477518 @default.
- W2333466121 hasAuthorship W2333466121A5039492144 @default.
- W2333466121 hasAuthorship W2333466121A5056993350 @default.
- W2333466121 hasAuthorship W2333466121A5059395063 @default.
- W2333466121 hasAuthorship W2333466121A5068203096 @default.
- W2333466121 hasBestOaLocation W23334661211 @default.
- W2333466121 hasConcept C120665830 @default.
- W2333466121 hasConcept C121332964 @default.
- W2333466121 hasConcept C126322002 @default.
- W2333466121 hasConcept C134018914 @default.
- W2333466121 hasConcept C2776390293 @default.
- W2333466121 hasConcept C2779256933 @default.
- W2333466121 hasConcept C2779279991 @default.
- W2333466121 hasConcept C61511704 @default.
- W2333466121 hasConcept C71315377 @default.
- W2333466121 hasConcept C71924100 @default.
- W2333466121 hasConceptScore W2333466121C120665830 @default.
- W2333466121 hasConceptScore W2333466121C121332964 @default.
- W2333466121 hasConceptScore W2333466121C126322002 @default.
- W2333466121 hasConceptScore W2333466121C134018914 @default.
- W2333466121 hasConceptScore W2333466121C2776390293 @default.
- W2333466121 hasConceptScore W2333466121C2779256933 @default.
- W2333466121 hasConceptScore W2333466121C2779279991 @default.
- W2333466121 hasConceptScore W2333466121C61511704 @default.
- W2333466121 hasConceptScore W2333466121C71315377 @default.
- W2333466121 hasConceptScore W2333466121C71924100 @default.
- W2333466121 hasIssue "7" @default.
- W2333466121 hasLocation W23334661211 @default.
- W2333466121 hasLocation W23334661212 @default.
- W2333466121 hasOpenAccess W2333466121 @default.
- W2333466121 hasPrimaryLocation W23334661211 @default.
- W2333466121 hasRelatedWork W2010635678 @default.
- W2333466121 hasRelatedWork W2023266651 @default.
- W2333466121 hasRelatedWork W2027210979 @default.
- W2333466121 hasRelatedWork W2027237635 @default.
- W2333466121 hasRelatedWork W2047281513 @default.
- W2333466121 hasRelatedWork W2076924632 @default.
- W2333466121 hasRelatedWork W2090176623 @default.
- W2333466121 hasRelatedWork W2101146068 @default.
- W2333466121 hasRelatedWork W2155643750 @default.
- W2333466121 hasRelatedWork W2981985604 @default.
- W2333466121 hasVolume "80" @default.
- W2333466121 isParatext "false" @default.
- W2333466121 isRetracted "false" @default.
- W2333466121 magId "2333466121" @default.
- W2333466121 workType "article" @default.