Matches in SemOpenAlex for { <https://semopenalex.org/work/W2333524189> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2333524189 endingPage "A73" @default.
- W2333524189 startingPage "A72" @default.
- W2333524189 abstract "Introduction: Pulmonary atresia with intact ventricular septum (PA/IVS) has been historically difficult to manage due to its heterogeneity in anatomy. Single ventricle palliation (SVP) of these patients (pts) has had varying outcomes and the risk factors for mortality have been elusive. The presence of right ventricular dependent coronary circulation (RVDCC) and associated coronary artery anomalies has had important impact in management of these pts in the intensive care unit and long term. Methods: Catheterization and medical records were reviewed in pts with PA/IVS who underwent SVP at our institution between 2000 and 2012. The primary outcome of interest was death or transplant. Based on initial angiography, pts with confirmed or strong suspicion of stenosis in ≥2 main coronary arteries or coronary ostial atresia were defined as having RVDCC while those with stenosis of only one main vessel or normal coronary anatomy as non-RVDCC. Results: Of 56 pts diagnosed with PA/IVS, 17 (30%) underwent SVP. All had severe right ventricular hypoplasia. Ten of the SVP pts (59%) were diagnosed with RVDCC (3 with ostial atresia), and 7 (41%) with non-RVDCC (5 with normal coronary anatomy and 2 with stenosis of one coronary artery). Sinusoids were present in all RVDCC and in 4 out of 7 non-RVDCC pts. Median follow up time was 8.2 years (0 months to 11.3 years). One patient in each group was lost to follow up. Five RVDCC pts died and 1 underwent transplant due to ischemia in the first 6 months of life. Four of the deaths, including the 3 pts with ostial atresia, occurred before discharge from first hospitalization. No deaths occurred after second stage palliation. Three of the 4 surviving RVDCC pts having undergone Fontan, although 2 demonstrated signs of cardiac ischemia (one by PET scan and another by ischemic cardiac arrest during diagnostic catheterization). No deaths or ischemic events occurred in non-RVDCC pts, 5 of whom have undergone completion of Fontan. Kaplan-Meier analysis demonstrated significantly better survival in non-RVDCC vs RVDCC pts (p=0.013). Conclusions: In pts with PA/IVS undergoing SVP, RVDCC is associated with high early in-hospital mortality. There should be early evaluation for cardiac transplant in pts with RVDCC. Mechanical circulatory support, as a bridge to transplant, should be considered in pts with signs of ischemia and heart failure. Non-RVDCC pts, including those with stenosis of a single coronary artery, have excellent long-term outcome in this series." @default.
- W2333524189 created "2016-06-24" @default.
- W2333524189 creator A5002965469 @default.
- W2333524189 creator A5008794363 @default.
- W2333524189 creator A5029822474 @default.
- W2333524189 creator A5040910044 @default.
- W2333524189 date "2013-12-01" @default.
- W2333524189 modified "2023-10-16" @default.
- W2333524189 title "311" @default.
- W2333524189 doi "https://doi.org/10.1097/01.ccm.0000439455.11353.3a" @default.
- W2333524189 hasPublicationYear "2013" @default.
- W2333524189 type Work @default.
- W2333524189 sameAs 2333524189 @default.
- W2333524189 citedByCount "0" @default.
- W2333524189 crossrefType "journal-article" @default.
- W2333524189 hasAuthorship W2333524189A5002965469 @default.
- W2333524189 hasAuthorship W2333524189A5008794363 @default.
- W2333524189 hasAuthorship W2333524189A5029822474 @default.
- W2333524189 hasAuthorship W2333524189A5040910044 @default.
- W2333524189 hasConcept C126322002 @default.
- W2333524189 hasConcept C164705383 @default.
- W2333524189 hasConcept C2776820930 @default.
- W2333524189 hasConcept C2778088351 @default.
- W2333524189 hasConcept C2778297461 @default.
- W2333524189 hasConcept C2778742706 @default.
- W2333524189 hasConcept C2778921608 @default.
- W2333524189 hasConcept C2780007028 @default.
- W2333524189 hasConcept C2780327212 @default.
- W2333524189 hasConcept C2781149206 @default.
- W2333524189 hasConcept C3019004856 @default.
- W2333524189 hasConcept C500558357 @default.
- W2333524189 hasConcept C71924100 @default.
- W2333524189 hasConceptScore W2333524189C126322002 @default.
- W2333524189 hasConceptScore W2333524189C164705383 @default.
- W2333524189 hasConceptScore W2333524189C2776820930 @default.
- W2333524189 hasConceptScore W2333524189C2778088351 @default.
- W2333524189 hasConceptScore W2333524189C2778297461 @default.
- W2333524189 hasConceptScore W2333524189C2778742706 @default.
- W2333524189 hasConceptScore W2333524189C2778921608 @default.
- W2333524189 hasConceptScore W2333524189C2780007028 @default.
- W2333524189 hasConceptScore W2333524189C2780327212 @default.
- W2333524189 hasConceptScore W2333524189C2781149206 @default.
- W2333524189 hasConceptScore W2333524189C3019004856 @default.
- W2333524189 hasConceptScore W2333524189C500558357 @default.
- W2333524189 hasConceptScore W2333524189C71924100 @default.
- W2333524189 hasLocation W23335241891 @default.
- W2333524189 hasOpenAccess W2333524189 @default.
- W2333524189 hasPrimaryLocation W23335241891 @default.
- W2333524189 hasRelatedWork W1576689636 @default.
- W2333524189 hasRelatedWork W1990973686 @default.
- W2333524189 hasRelatedWork W2009510980 @default.
- W2333524189 hasRelatedWork W2024869830 @default.
- W2333524189 hasRelatedWork W2027791684 @default.
- W2333524189 hasRelatedWork W2068791151 @default.
- W2333524189 hasRelatedWork W2080648445 @default.
- W2333524189 hasRelatedWork W2090198556 @default.
- W2333524189 hasRelatedWork W2226249931 @default.
- W2333524189 hasRelatedWork W3173484483 @default.
- W2333524189 hasVolume "41" @default.
- W2333524189 isParatext "false" @default.
- W2333524189 isRetracted "false" @default.
- W2333524189 magId "2333524189" @default.
- W2333524189 workType "article" @default.