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- W2333705457 abstract "Background and aims: Hypothermia is a recent and popular treatment approach for the treatment of hypoxic ischemic encephalopathy (HIE). On the other hand, Ischemia modified albumin (IMA) is a new marker for ischemic process. However, effect of hypothermia on newborns with HIE who underwent hypothermia was not investigated previously. Methods: Between 2012 and 2013, newborns hospitalized for HIE were prospectively followed in our NICU. IMA, total antioxidant status (TOS), haemogram and routine biochemical parameters and blood gas analyses were prospectively collected both before the hypothermia and at the end of the hypothermia in newborns with HIE. Statistical analysis was performed by SPSS v.11. Paired sampled t test was used to compare the results. “p” value < 0.05 was considered as significant.IRB approval was taken. Results: There were 27 newborns with HIE hospitalized in NICU during the study period. The mean gestational age was 39.54 ± 0.99 week and the mean birth weight was 3475 ± 495 gr. IMA levels were significantly higher in newborn with HIE before the hypothermia compared with at the end of the hypothermia (96.49 ± 5.32 vs. 94.64 ± 5.52, p<0.001). Conclusions: Hypothermia has a positive impact on the levels of IMA in newborns with HIE. Clinical significance of this observation should be investigated in further studies." @default.
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- W2333705457 date "2014-05-01" @default.
- W2333705457 modified "2023-10-18" @default.
- W2333705457 title "ABSTRACT 308" @default.
- W2333705457 doi "https://doi.org/10.1097/01.pcc.0000449034.97427.8c" @default.
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