FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2333977052> ?p ?o ?g. }

• W2333977052 endingPage "6601" @default.
• W2333977052 startingPage "6588" @default.
• W2333977052 abstract "We investigated in vitro the effect of low-frequency and low-energy ultrasound (LFLEU) on apoptosis of an overexpressed HSP27 human aortic smooth muscle cell (HASMC) line. A frequency of 42.6 kHz was used in all experiments. HASMC were exposed to ultrasound and cell viability was evaluated by MTT reduction. Overexpressed HSP27-HASMC was constructed on a pcDNA3.1 vector. Apoptosis was determined 24 h after treatment by flow cytometry; gene display was evaluated with Affimax chips, and HSP27 mRNA and protein expression levels were measured by RT-PCR and Western blotting. The apoptosis rate (at 30 s) was significantly lower in HASMC transfected with HSP27 (7.14 ± 1.73%), compared with cells transfected with a mock plasmid (17.31 ± 2.72%) or a control group (14.23 ± 2.77%), indicating a protective function for apoptosis induced by LFLEU. Gene display analysis showed that caspase-9 expression in HSP27 cell lines was downregulated and caspase-3 upregulated. However, RT-PCR and Western blotting analysis indicated that both caspase-9 and caspase-3 were inhibited at both the mRNA and protein levels. We suggest that overexpressed HSP27 is capable of protecting the LFLEU from apoptosis and that the pathway for this protection is via downregulated caspase-9 and caspase-3 expression." @default.
• W2333977052 created "2016-06-24" @default.
• W2333977052 creator A5034407018 @default.
• W2333977052 creator A5048200579 @default.
• W2333977052 creator A5060995251 @default.
• W2333977052 creator A5073495667 @default.
• W2333977052 creator A5076031419 @default.
• W2333977052 date "2013-01-01" @default.
• W2333977052 modified "2023-09-25" @default.
• W2333977052 title "Overexpression of HSP27 in cultured human aortic smooth muscular cells reduces apoptosis induced by low-frequency and low-energy ultrasound by inhibition of an intrinsic pathway" @default.
• W2333977052 cites W108200661 @default.
• W2333977052 cites W1489733307 @default.
• W2333977052 cites W1535468221 @default.
• W2333977052 cites W1547300732 @default.
• W2333977052 cites W1968629782 @default.
• W2333977052 cites W1968663827 @default.
• W2333977052 cites W1969081544 @default.
• W2333977052 cites W1969639222 @default.
• W2333977052 cites W1970724938 @default.
• W2333977052 cites W1986022624 @default.
• W2333977052 cites W1991666936 @default.
• W2333977052 cites W1996807630 @default.
• W2333977052 cites W1997762479 @default.
• W2333977052 cites W2012141576 @default.
• W2333977052 cites W2020000532 @default.
• W2333977052 cites W2020859520 @default.
• W2333977052 cites W2031969926 @default.
• W2333977052 cites W2033523236 @default.
• W2333977052 cites W2041604464 @default.
• W2333977052 cites W2052128923 @default.
• W2333977052 cites W2057627932 @default.
• W2333977052 cites W2059541988 @default.
• W2333977052 cites W2068254519 @default.
• W2333977052 cites W2072474414 @default.
• W2333977052 cites W2074332495 @default.
• W2333977052 cites W2075585174 @default.
• W2333977052 cites W2076314631 @default.
• W2333977052 cites W2089400513 @default.
• W2333977052 cites W2092822223 @default.
• W2333977052 cites W2094599199 @default.
• W2333977052 cites W2094697297 @default.
• W2333977052 cites W2121712948 @default.
• W2333977052 cites W2124684134 @default.
• W2333977052 cites W2136029021 @default.
• W2333977052 cites W2140735579 @default.
• W2333977052 cites W2144326073 @default.
• W2333977052 cites W2164169011 @default.
• W2333977052 cites W2178113031 @default.
• W2333977052 cites W2343047716 @default.
• W2333977052 doi "https://doi.org/10.4238/2013.december.11.10" @default.
• W2333977052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24391005" @default.
• W2333977052 hasPublicationYear "2013" @default.
• W2333977052 type Work @default.
• W2333977052 sameAs 2333977052 @default.
• W2333977052 citedByCount "4" @default.
• W2333977052 countsByYear W23339770522016 @default.
• W2333977052 countsByYear W23339770522017 @default.
• W2333977052 countsByYear W23339770522018 @default.
• W2333977052 crossrefType "journal-article" @default.
• W2333977052 hasAuthorship W2333977052A5034407018 @default.
• W2333977052 hasAuthorship W2333977052A5048200579 @default.
• W2333977052 hasAuthorship W2333977052A5060995251 @default.
• W2333977052 hasAuthorship W2333977052A5073495667 @default.
• W2333977052 hasAuthorship W2333977052A5076031419 @default.
• W2333977052 hasBestOaLocation W23339770521 @default.
• W2333977052 hasConcept C104317684 @default.
• W2333977052 hasConcept C153911025 @default.
• W2333977052 hasConcept C185592680 @default.
• W2333977052 hasConcept C190283241 @default.
• W2333977052 hasConcept C205260736 @default.
• W2333977052 hasConcept C2776415932 @default.
• W2333977052 hasConcept C2779559962 @default.
• W2333977052 hasConcept C2780783641 @default.
• W2333977052 hasConcept C53227056 @default.
• W2333977052 hasConcept C54009773 @default.
• W2333977052 hasConcept C54355233 @default.
• W2333977052 hasConcept C553184892 @default.
• W2333977052 hasConcept C55493867 @default.
• W2333977052 hasConcept C62112901 @default.
• W2333977052 hasConcept C68991219 @default.
• W2333977052 hasConcept C81885089 @default.
• W2333977052 hasConcept C85265743 @default.
• W2333977052 hasConcept C86803240 @default.
• W2333977052 hasConceptScore W2333977052C104317684 @default.
• W2333977052 hasConceptScore W2333977052C153911025 @default.
• W2333977052 hasConceptScore W2333977052C185592680 @default.
• W2333977052 hasConceptScore W2333977052C190283241 @default.
• W2333977052 hasConceptScore W2333977052C205260736 @default.
• W2333977052 hasConceptScore W2333977052C2776415932 @default.
• W2333977052 hasConceptScore W2333977052C2779559962 @default.
• W2333977052 hasConceptScore W2333977052C2780783641 @default.
• W2333977052 hasConceptScore W2333977052C53227056 @default.
• W2333977052 hasConceptScore W2333977052C54009773 @default.
• W2333977052 hasConceptScore W2333977052C54355233 @default.
• W2333977052 hasConceptScore W2333977052C553184892 @default.
• W2333977052 hasConceptScore W2333977052C55493867 @default.
• W2333977052 hasConceptScore W2333977052C62112901 @default.
• W2333977052 hasConceptScore W2333977052C68991219 @default.

• next