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• W2334007793 abstract "To evaluate the structural stability of recoverin, a member of the neuronal calcium sensor family, the effect of temperature, myristoylation, and calcium:protein molar ratio on its secondary structure has been studied by transmission infrared spectroscopy. On the basis of the data, the protein predominantly adopts α-helical structures (∼50–55%) with turns, unordered structures, and β-sheets at 25 °C. The data show no significant impact of the presence of calcium and myristoylation on secondary structure. It is found that, in the absence of calcium, recoverin denatures and self-aggregates while being heated, with the formation of intermolecular antiparallel β-sheets. The nonmyristoylated protein (Rec-nMyr) exhibits a lower temperature threshold of aggregation and a higher intermolecular β-sheet content at 65 °C than the myristoylated protein (Rec-Myr). The former thus appears to be less thermally stable than the latter. In the presence of excess calcium ions (calcium:protein ratio of 10), the protein is thermally stable up to 65 °C with no significant conformational change, the presence of the myristoyl chain having no effect on the thermal stability of recoverin under these conditions. A decrease in the thermal stability of recoverin is observed as the calcium:protein molar ratio decreases, with Rec-nMyr being less stable than Rec-Myr. The data overall suggest that a minimal number of coordinated calcium ions is necessary to fully stabilize the structure of recoverin and that, when bound to the membrane, i.e., when the myristoyl chain protrudes from the interior pocket, recoverin should be more stable than in a Ca-free solution, i.e., when the myristoyl chain is sequestered in the interior." @default.
• W2334007793 created "2016-06-24" @default.
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• W2334007793 date "2013-12-23" @default.
• W2334007793 modified "2023-10-16" @default.
• W2334007793 title "The Thermal Stability of Recoverin Depends on Calcium Binding and Its Myristoyl Moiety As Revealed by Infrared Spectroscopy" @default.
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• W2334007793 cites W1945182923 @default.
• W2334007793 cites W1966412526 @default.
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• W2334007793 cites W1969971056 @default.
• W2334007793 cites W1970070873 @default.
• W2334007793 cites W1972523592 @default.
• W2334007793 cites W1975038690 @default.
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• W2334007793 cites W1998180354 @default.
• W2334007793 cites W2000416626 @default.
• W2334007793 cites W2001503045 @default.
• W2334007793 cites W2007030262 @default.
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• W2334007793 cites W2026559340 @default.
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• W2334007793 cites W2032151451 @default.
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• W2334007793 doi "https://doi.org/10.1021/bi401336g" @default.
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