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- W2334019801 abstract "Soft rot is a serious disease among vegetable crops that leads to high rate of economic loss to farmers. The disease is mainly caused by gram negative bacteria belonging to Pectobacterium species. The main symptom is necrosis due to degradation of cell wall by the activity of certain exo-enzymes (Plant Cell Wall Degrading Enzymes) which is produced by the bacteria in accordance with quorum sensing and signal transduction. The present study focused to control the synthesis of autoinducer called Acyl homoserine lactone, which modulates quorum sensing through the inhibition of Methionine S-adenosyl transferase (S-adenosyl methionine synthase) and Acyl homoserine lactone synthase enzymes. The inhibitory activities of Cycloleucine on Methionine S-adenosyl transferase and S-adenosyl methionine analogs on Acyl homoserine lactone synthase were studied by docking method using AutoDock 4.2. The results obtained indicate that the organic molecules used for the inhibition of targeted enzymes may be the best choice for the control of soft rot in vegetable crops." @default.
- W2334019801 created "2016-06-24" @default.
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- W2334019801 date "2013-01-01" @default.
- W2334019801 modified "2023-10-06" @default.
- W2334019801 title "In silico approach to prevent soft rot in vegetable crops" @default.
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- W2334019801 doi "https://doi.org/10.9790/2380-0330104" @default.
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