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- W2334043909 abstract "BMS-911543 is a complex pyrrolopyridine investigated as a potential treatment for myeloproliferative disorders. The development of a short and efficient synthesis of this molecule is described. During the course of our studies, a Ni-mediated C–N bond formation was invented, which enabled the rapid construction of the highly substituted 2-aminopyridine core. The synthesis of this complex, nitrogen-rich heterocycle was accomplished in only eight steps starting from readily available materials." @default.
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- W2334043909 date "2015-05-01" @default.
- W2334043909 modified "2023-10-18" @default.
- W2334043909 title "Ni-Catalyzed C–H Functionalization in the Formation of a Complex Heterocycle: Synthesis of the Potent JAK2 Inhibitor BMS-911543" @default.
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- W2334043909 doi "https://doi.org/10.1021/acs.joc.5b00572" @default.
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