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- W2334094600 abstract "An intimate association between adrenal protein synthesis and the ACTH stimulation of corticosteroid production has been suggested on the basis of several careful studies (1, 2). The exact relationship between protein synthesis and hormone action has not been clearly defined, and most of the attempts to study this relationship have been done in vitro utilizing adrenals from animal sources. A previous attempt to study the association between protein synthesis and adrenal function in man was done in vivo with patients receiving fluorinated pyrimidines as cancer chemotherapy (3). Under the conditions of the study, it was impossible to demonstrate that the fluorinated pyrimidines had an inhibitory effect on adrenal function. Since species differences exist with regard to adrenal function, it was of interest to study the relationship in man between adrenal protein synthesis and corticosteroid production in vitro.Material and Methods. Adrenals were obtained at the time of operation from three patients undergoin..." @default.
- W2334094600 created "2016-06-24" @default.
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- W2334094600 date "1970-07-01" @default.
- W2334094600 modified "2023-10-14" @default.
- W2334094600 title "Adrenal Protein Synthesis and Corticosteroid Production in Man" @default.
- W2334094600 doi "https://doi.org/10.3181/00379727-134-34901" @default.
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