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• W2334137210 abstract "The direct correlation between glucose levels and cardiovascular disease in individuals with type 2 diabetes can now be applied to individuals that share an abnormal metabolic milieu similar to that found in central obesity, the metabolic syndrome, and type 2 diabetes. Premature macrovascular complications with a very high morbidity and mortality rate can be found in these nondiabetic populations. The typical phenotype has visceral or central obesity, excess of free fatty acids, insulin resistance, increased insulin secretion, and hypertension. A more complex metabolic-cardiovascular syndrome develops that includes dyslipidemia, abnormal production of cytokines, chronic inflammatory state, and abnormal coagulation. The interplay of all these cardiovascular risk factors is responsible for the accelerated atherosclerotic process. The different terminologies used for populations sharing this common ground for premature cardiovascular disease now generally accepted as the metabolic syndrome, are also discussed. Aggressive insulin treatment during acute illness in individuals with the abnormal metabolic milieu is beneficial. Insulin treatment is changing from using insulin as a hormone to treat only severe hyperglycemia, to a new paradigm using insulin in high doses as a drug. Aggressive insulin regimens should be used to treat only minimal elevations of blood glucose or to prevent hyperglycemia. The newly observed properties of insulin are reviewed which include suppression of inflammatory cytokines and adhesion molecules, improved hemostasis, and other cardiac beneficial effects. The concomitant administration of intravenous glucose and insulin permits the administration of higher insulin doses that can result in improved outcome due to its nonglycemic-related benefits. The use of aggressive insulin therapy requires both better and more cost-effective algorithms to successfully treat this high-risk population during acute illness." @default.
• W2334137210 created "2016-06-24" @default.
• W2334137210 creator A5027111712 @default.
• W2334137210 creator A5054772751 @default.
• W2334137210 date "2003-09-01" @default.
• W2334137210 modified "2023-10-18" @default.
• W2334137210 title "Using Insulin as a Drug Rather Than as a Replacement Hormone During Acute Illness" @default.
• W2334137210 cites W103954886 @default.
• W2334137210 cites W124335555 @default.
• W2334137210 cites W1511509126 @default.
• W2334137210 cites W1840840071 @default.
• W2334137210 cites W1966523819 @default.
• W2334137210 cites W1969623264 @default.
• W2334137210 cites W1972848525 @default.
• W2334137210 cites W1980717583 @default.
• W2334137210 cites W1981441027 @default.
• W2334137210 cites W1984155998 @default.
• W2334137210 cites W1984191109 @default.
• W2334137210 cites W1986190949 @default.
• W2334137210 cites W1986349550 @default.
• W2334137210 cites W1987651688 @default.
• W2334137210 cites W1989934249 @default.
• W2334137210 cites W1990588947 @default.
• W2334137210 cites W1992255868 @default.
• W2334137210 cites W1992802871 @default.
• W2334137210 cites W1999775886 @default.
• W2334137210 cites W2000634649 @default.
• W2334137210 cites W2002011371 @default.
• W2334137210 cites W2008674682 @default.
• W2334137210 cites W2010226239 @default.
• W2334137210 cites W2012928421 @default.
• W2334137210 cites W2014663082 @default.
• W2334137210 cites W2014759828 @default.
• W2334137210 cites W2014877159 @default.
• W2334137210 cites W2015546180 @default.
• W2334137210 cites W2020258589 @default.
• W2334137210 cites W2025062210 @default.
• W2334137210 cites W2027065577 @default.
• W2334137210 cites W2027702390 @default.
• W2334137210 cites W2029366316 @default.
• W2334137210 cites W2030417531 @default.
• W2334137210 cites W2033704972 @default.
• W2334137210 cites W2036762211 @default.
• W2334137210 cites W2037411642 @default.
• W2334137210 cites W2040823879 @default.
• W2334137210 cites W2041339005 @default.
• W2334137210 cites W2044594443 @default.
• W2334137210 cites W2045658220 @default.
• W2334137210 cites W2046096086 @default.
• W2334137210 cites W2054283440 @default.
• W2334137210 cites W2056629988 @default.
• W2334137210 cites W2057651652 @default.
• W2334137210 cites W2058536977 @default.
• W2334137210 cites W2060449981 @default.
• W2334137210 cites W2060462962 @default.
• W2334137210 cites W2064754310 @default.
• W2334137210 cites W2067096633 @default.
• W2334137210 cites W2067184340 @default.
• W2334137210 cites W2069427959 @default.
• W2334137210 cites W2071407810 @default.
• W2334137210 cites W2076186944 @default.
• W2334137210 cites W2083175639 @default.
• W2334137210 cites W2085087376 @default.
• W2334137210 cites W2091878942 @default.
• W2334137210 cites W2094642452 @default.
• W2334137210 cites W2100500261 @default.
• W2334137210 cites W2102348011 @default.
• W2334137210 cites W2106276823 @default.
• W2334137210 cites W2106603497 @default.
• W2334137210 cites W2107545755 @default.
• W2334137210 cites W2108462699 @default.
• W2334137210 cites W2110806627 @default.
• W2334137210 cites W2117268230 @default.
• W2334137210 cites W2120852510 @default.
• W2334137210 cites W2123744385 @default.
• W2334137210 cites W2126317966 @default.
• W2334137210 cites W2128722360 @default.
• W2334137210 cites W2131556432 @default.
• W2334137210 cites W2132594773 @default.
• W2334137210 cites W2134644322 @default.
• W2334137210 cites W2134652276 @default.
• W2334137210 cites W2147332678 @default.
• W2334137210 cites W2153157231 @default.
• W2334137210 cites W2156706409 @default.
• W2334137210 cites W2158009122 @default.
• W2334137210 cites W2158822657 @default.
• W2334137210 cites W2162231109 @default.
• W2334137210 cites W2163567504 @default.
• W2334137210 cites W2171028311 @default.
• W2334137210 cites W2191654227 @default.
• W2334137210 cites W2320729047 @default.
• W2334137210 cites W2324841714 @default.
• W2334137210 cites W2330505590 @default.
• W2334137210 cites W2331176038 @default.
• W2334137210 cites W2331274940 @default.
• W2334137210 cites W2332951586 @default.
• W2334137210 cites W2334309509 @default.
• W2334137210 cites W2379617790 @default.
• W2334137210 cites W2913709946 @default.
• W2334137210 cites W303812557 @default.

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