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- W2334167805 abstract "A simple reversed phase HPLC method have been successfully developed and validated for the quantitative determination of enalapril maleate (ENP) in bulk material, pharmaceutical formulation and serum. Purospher Start C 18 (250 cm x 4.6 mm, 5 μm) and Hypersil, ODS columns were used. The mobile phase, methanol-acetonitrile-water (70:30v/v pH 3.5 adjusted by phosphoric acid), was delivered at a flow rate of 1 mLmin -1 , eluent was monitored using UV detector at 215 nm. The proposed method is specific, accurate (99-102%), precise (intra-day and inter-day variation 0.07-1.25%) and linearity (R 2 >0.999) within the desired range 2.5-100 μgmL -1 concentration. The detection limit and quantification 3.9 ngmL -1 and 12 ngmL -1 respectively. The anticipated method is applicable to routine analysis of ENP in pharmaceutical formulations as well as in human serum samples." @default.
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- W2334167805 date "2012-01-01" @default.
- W2334167805 modified "2023-10-12" @default.
- W2334167805 title "HPLC-UV Method for the Determination of Enalapril in Bulk, Pharmaceutical Formulations and Serum" @default.
- W2334167805 doi "https://doi.org/10.4172/2155-9872.1000130" @default.
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