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- W2334173020 abstract "OBJECTIVE To study the resistant mechanisms in a Burkholderia multivorans(BUM) clinical strain.METHODS The susceptibility to antimicrobial agents were detected by MIC.The 16S rRNA and 39 resistant-related genes including 29 β-lactamases genes,6 aminoglycoside-modifying enzymes(AMEs)genes,qacE△1-sul1 and 3 intergrons intⅠ1,2,3) were measured by PCR,and verified by DNA sequencing.RESULTS The strain was BUM by 16S rRNA-PCR-DNA sequencing;it was susceptible to piperacillin,aztreonam,cefotaxime,ceftazidime,cefepime,meropenem,ciprofloxacin,levofloxacin,and trimethoprim/sulfamethoxazole,but resistant to ampicillin,cefazilin,imipenem,colistin,gentamicin and amikacin;in the strain,there were positive of 3 kinds of resistant-related genes(blaCARB,ant(3″)-Ⅰ and intⅠ1).Twenty-eight kinds of β-lactamases genes,5 kinds of AMEs genes,one qacE△1-sul1 gene 2 kinds of intⅠ(intⅠ2 and intⅠ3) genes were negative.CONCLUSION The multi-resistant mechanisms and of BUM,mainly relate to 3 kinds of resistant-related genes blaCARB,ant(3″)-Ⅰ and intⅠ1." @default.
- W2334173020 created "2016-06-24" @default.
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- W2334173020 date "2010-01-01" @default.
- W2334173020 modified "2023-09-24" @default.
- W2334173020 title "Detection of blaCARB-2 and ant (3″)- I of resistant-related genes in a Burkholderia multivorans strain." @default.
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