SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2334179310> ?p ?o ?g. }

Showing items 1 to 81 of 81 with 100 items per page.

W2334179310 endingPage "S204" @default.
W2334179310 startingPage "S204" @default.
W2334179310 abstract "The Integrated Assessment Scheme (IAS) defines weight factors for each piece of toxicological information under REACH in an Integrated Testing Strategy. This IAS is illustrated on skin irritation for Classification and Labelling (C&L) for five substances and using mostly (Q)SAR models. The models are the BfR Rulebase, Derek for Windows and TOPKAT, read across and pH-rules. The weight factors derived in the IAS show that for peracetic-acid and pentabromodiphenylether the C&L decision could be easily made. For bisphenol A additional information on read across was used to finalise a decision on C&L, while for methylphenyl-diisocyanate additional expert judgement was needed. For allylheptanoate only the TOPKAT prediction was in the applicability domain, which was insufficient on its own. Therefore, other non guideline testing information was used and in vitro testing results. The above examples on skin irritation information show how the IAS can aid in the decision making process and how it adds to the ToxRTool and the ITS of Hoffmann et al. on the same endpoint and similar methods." @default.
W2334179310 created "2016-06-24" @default.
W2334179310 creator A5000772555 @default.
W2334179310 creator A5023471516 @default.
W2334179310 creator A5034355524 @default.
W2334179310 creator A5056503862 @default.
W2334179310 creator A5058334403 @default.
W2334179310 creator A5061011678 @default.
W2334179310 creator A5064793035 @default.
W2334179310 creator A5084057589 @default.
W2334179310 date "2013-08-01" @default.
W2334179310 modified "2023-09-25" @default.
W2334179310 title "Applicability of in silico models for the prediction of the sensitization potential of industrial chemicals" @default.
W2334179310 doi "https://doi.org/10.1016/j.toxlet.2013.05.480" @default.
W2334179310 hasPublicationYear "2013" @default.
W2334179310 type Work @default.
W2334179310 sameAs 2334179310 @default.
W2334179310 citedByCount "0" @default.
W2334179310 crossrefType "journal-article" @default.
W2334179310 hasAuthorship W2334179310A5000772555 @default.
W2334179310 hasAuthorship W2334179310A5023471516 @default.
W2334179310 hasAuthorship W2334179310A5034355524 @default.
W2334179310 hasAuthorship W2334179310A5056503862 @default.
W2334179310 hasAuthorship W2334179310A5058334403 @default.
W2334179310 hasAuthorship W2334179310A5061011678 @default.
W2334179310 hasAuthorship W2334179310A5064793035 @default.
W2334179310 hasAuthorship W2334179310A5084057589 @default.
W2334179310 hasConcept C107908354 @default.
W2334179310 hasConcept C111919701 @default.
W2334179310 hasConcept C119857082 @default.
W2334179310 hasConcept C124101348 @default.
W2334179310 hasConcept C134306372 @default.
W2334179310 hasConcept C164126121 @default.
W2334179310 hasConcept C17744445 @default.
W2334179310 hasConcept C178790620 @default.
W2334179310 hasConcept C185592680 @default.
W2334179310 hasConcept C199539241 @default.
W2334179310 hasConcept C2776548248 @default.
W2334179310 hasConcept C2777309684 @default.
W2334179310 hasConcept C33923547 @default.
W2334179310 hasConcept C36503486 @default.
W2334179310 hasConcept C41008148 @default.
W2334179310 hasConcept C533411734 @default.
W2334179310 hasConcept C98045186 @default.
W2334179310 hasConceptScore W2334179310C107908354 @default.
W2334179310 hasConceptScore W2334179310C111919701 @default.
W2334179310 hasConceptScore W2334179310C119857082 @default.
W2334179310 hasConceptScore W2334179310C124101348 @default.
W2334179310 hasConceptScore W2334179310C134306372 @default.
W2334179310 hasConceptScore W2334179310C164126121 @default.
W2334179310 hasConceptScore W2334179310C17744445 @default.
W2334179310 hasConceptScore W2334179310C178790620 @default.
W2334179310 hasConceptScore W2334179310C185592680 @default.
W2334179310 hasConceptScore W2334179310C199539241 @default.
W2334179310 hasConceptScore W2334179310C2776548248 @default.
W2334179310 hasConceptScore W2334179310C2777309684 @default.
W2334179310 hasConceptScore W2334179310C33923547 @default.
W2334179310 hasConceptScore W2334179310C36503486 @default.
W2334179310 hasConceptScore W2334179310C41008148 @default.
W2334179310 hasConceptScore W2334179310C533411734 @default.
W2334179310 hasConceptScore W2334179310C98045186 @default.
W2334179310 hasLocation W23341793101 @default.
W2334179310 hasOpenAccess W2334179310 @default.
W2334179310 hasPrimaryLocation W23341793101 @default.
W2334179310 hasRelatedWork W1864954421 @default.
W2334179310 hasRelatedWork W2022068521 @default.
W2334179310 hasRelatedWork W2035737210 @default.
W2334179310 hasRelatedWork W2109570758 @default.
W2334179310 hasRelatedWork W2348097614 @default.
W2334179310 hasRelatedWork W2362192218 @default.
W2334179310 hasRelatedWork W2370652759 @default.
W2334179310 hasRelatedWork W2623347760 @default.
W2334179310 hasRelatedWork W3034138874 @default.
W2334179310 hasRelatedWork W831794578 @default.
W2334179310 hasVolume "221" @default.
W2334179310 isParatext "false" @default.
W2334179310 isRetracted "false" @default.
W2334179310 magId "2334179310" @default.
W2334179310 workType "article" @default.