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• W2334281493 abstract "In Brief OBJECTIVE: To estimate the extent of Staphylococcus aureus vaginal-rectal colonization among pregnant women as severe S aureus infections have emerged in pregnant and postpartum women and infants. METHODS: We conducted a prospective surveillance study for methicillin-sensitive S aureus and methicillin-resistant S aureus on all routine de-identified vaginal-rectal prenatal group B streptococcus (GBS) screening cultures submitted to the microbiology laboratory of a tertiary-care facility from January to July 2005. Standard microbiologic techniques and molecular analyses were used to detect community-associated methicillin-resistant S aureus strains. As opposed to health care–associated methicillin-resistant S aureus isolates, community-associated methicillin-resistant S aureus isolates were defined as those possessing the type IV or type V staphylococcal chromosomal cassette mec element and usually lacking a multidrug-resistant phenotype. RESULTS: A total of 2,963 GBS screening cultures were analyzed, from which 743 (25.1%, 95% confidence interval [CI] 23.5–26.7%) GBS isolates and 507 (17.1%, 95% CI 15.7–18.5%) S aureus isolates were identified. Group B streptococcus colonization was significantly associated with S aureus colonization (prevalence odds ratio 2.1, 95% CI 1.7–2.5, P<.001). Of the S aureus isolates, 14 (2.8%, 95% CI 1.4–4.2%) were methicillin-resistant, and 13 of these were determined to be community-associated methicillin-resistant S aureus. CONCLUSION: The prevalence of S aureus colonization identified in GBS screening cultures from pregnant women was substantial and associated with GBS co-colonization. Although we do not advocate routine screening of pregnant women for methicillin-sensitive S aureus and methicillin-resistant S aureus colonization, we recommend continued monitoring of both methicillin-sensitive S aureus and methicillin-resistant S aureus infections in this population and their infants. LEVEL OF EVIDENCE: II-3 The prevalence of Staphylococcus aureus vaginal-rectal colonization among pregnant women is 17.1%, and community-associated, methicillin-resistant S. aureus in the vaginal-rectal areas was detected." @default.
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• W2334281493 date "2006-09-01" @default.
• W2334281493 modified "2023-09-25" @default.
• W2334281493 title "Prevalence of Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus in Pregnant Women" @default.
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• W2334281493 doi "https://doi.org/10.1097/01.aog.0000227964.22439.e3" @default.
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