FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2334286003> ?p ?o ?g. }

• W2334286003 abstract "Event Abstract Back to Event Properties of Silicone fluids before and after purification Can B. Hu1* and Mike Lowery1* 1 Abbott Medical Optics, United States Introduction: Silicone is a widely used biomaterial[1]. For ophthalmologic applications such as intraocular lenses (IOLs), many properties such as amount of leachables, clarity, refractive index (RI) and viscosity are all important factors for the IOL design. Freshly synthesized high RI silicone fluid usually needs to go through the filtration[2] process to improve the clarity; however, filtration alone can’t remove the low molecular weight species which may leach out after long term implantation. Purification of silicone fluid would be important to remove the undesired low molecular weight species. In this study, properties of silicone fluid before and after purification by solvent washing process are discussed. Material and Methods: High molecular weight silicone with refractive index of 1.47±0.01 was synthesized by anionic ring-opening polymerization[3]-[5]. After filtration through 0.2 µm PTFE filters, silicone fluid was purified by solvent washing process to remove low molecular weight species. Washing process was repeated multiple times (3X and 5X) to check the effect of purification on properties of refractive index (RI), Abbe number, UV-Vis percent transmission (%T), haze level and viscosity. Results: Table 1 shows RI and Abbe number before and after multiple purification process. Although RI of purified silicone fluid was slightly dropped (0.0015 and 0.0019 respectively with 3 and 5 times purification when compared to the filtered control sample only, nevertheless, the difference is significant with p value <0.05 for both purification processes. Abbe number increased slightly after purification. The haze levels before and after purification was summarized in Table 2. It was found that haze level was increased from 2.6 to 3.9 and 5.2 respectively after 3 times and 5 times purification. Although the haze difference of silicone fluid after purification was statistically significant, however, the difference was difficult to tell by naked eyes. It was found that haze level increased with number of purification process. Table 1 and 2. RI, Abbe number and Haze level of silicone fluid before and after purification. An overlap UV/Vis scan of silicone fluid before and after multiple purification process was shown in Figure 1. As in Figure 1, percent transmission (%T) of UV/Vis of purified silicone fluids were also slightly lower than that of non-purified control sample. This observation is consistent with the results of haze study and confirmed our previous study[2]. Figure 1. UV/Vis scans of silicone before and after purification Results of viscosity measurement of silicone fluid before and after purification were summarized in Table 3. It was found that viscosity increased significantly after purification which indicated that low molecular weight species were removed effectively. Table 3. Viscosity of silicone fluid before and after filtration Conclusions: In this study, we found that purification is a very effective method to remove the low molecular weight species of silicone fluid as indicated by the significantly increased the viscosity of silicone fluid. However, other properties such as refractive index, abbe number, haze level and percent transmission of silicone are also impacted by the purification process as well and worth studying further. Thanks approval from Abbott Medical Optics to presented this work SC2015CT0038References:[1] J. H. Son, C Kim and J. W Yang “Comparison of experimental porous silicone implants” Graefes Arch Clin Exp Ophthalmol 250 879-885 (2012).[2] C. B. Hu and D. Urbaniak “UV-Vis Transimission and Haze Study of Silicone Fluids”, SFB Ann Mtg., 4 (2014)[3] C. B. Hu, D. Pham, M. Lowery and R. Jain “Design of Silicone Materials for Ophthalmic Application”, Soc. Biomat. 35th Ann. Mtg., 90 (2011).[4] C. B. Hu “Rheological and Related properties of Silicone”, 9th World Biomaterials Congress (2012).[5] M. F. Schatz and K. Howden, “Purification of silicone oils for Fluid experiments” Exp in Fluids 19 p359-361 (1995) Keywords: biomaterial, material design, Polymeric material, IOLs Conference: 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May, 2016. Presentation Type: Poster Topic: Biomaterials for ophthalmic applications Citation: Hu CB and Lowery M (2016). Properties of Silicone fluids before and after purification. Front. Bioeng. Biotechnol. Conference Abstract: 10th World Biomaterials Congress. doi: 10.3389/conf.FBIOE.2016.01.01577 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 27 Mar 2016; Published Online: 30 Mar 2016. * Correspondence: Dr. Can B Hu, Abbott Medical Optics, Santa Ana, CA, United States, Can.Hu@abbott.com Dr. Mike Lowery, Abbott Medical Optics, Santa Ana, CA, United States, Mike.Lowery@abbott.com Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Can B Hu Mike Lowery Google Can B Hu Mike Lowery Google Scholar Can B Hu Mike Lowery PubMed Can B Hu Mike Lowery Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
• W2334286003 created "2016-06-24" @default.
• W2334286003 creator A5017894324 @default.
• W2334286003 creator A5070660878 @default.
• W2334286003 date "2016-01-01" @default.
• W2334286003 modified "2023-10-18" @default.
• W2334286003 title "Properties of Silicone fluids before and after purification" @default.
• W2334286003 doi "https://doi.org/10.3389/conf.fbioe.2016.01.01577" @default.
• W2334286003 hasPublicationYear "2016" @default.
• W2334286003 type Work @default.
• W2334286003 sameAs 2334286003 @default.
• W2334286003 citedByCount "0" @default.
• W2334286003 crossrefType "journal-article" @default.
• W2334286003 hasAuthorship W2334286003A5017894324 @default.
• W2334286003 hasAuthorship W2334286003A5070660878 @default.
• W2334286003 hasBestOaLocation W23342860031 @default.
• W2334286003 hasConcept C105795698 @default.
• W2334286003 hasConcept C127172972 @default.
• W2334286003 hasConcept C128489963 @default.
• W2334286003 hasConcept C159985019 @default.
• W2334286003 hasConcept C178790620 @default.
• W2334286003 hasConcept C181199279 @default.
• W2334286003 hasConcept C185592680 @default.
• W2334286003 hasConcept C188027245 @default.
• W2334286003 hasConcept C192562407 @default.
• W2334286003 hasConcept C193363816 @default.
• W2334286003 hasConcept C2775952280 @default.
• W2334286003 hasConcept C2779769944 @default.
• W2334286003 hasConcept C2780471494 @default.
• W2334286003 hasConcept C33923547 @default.
• W2334286003 hasConcept C43617362 @default.
• W2334286003 hasConcept C44228677 @default.
• W2334286003 hasConcept C521977710 @default.
• W2334286003 hasConceptScore W2334286003C105795698 @default.
• W2334286003 hasConceptScore W2334286003C127172972 @default.
• W2334286003 hasConceptScore W2334286003C128489963 @default.
• W2334286003 hasConceptScore W2334286003C159985019 @default.
• W2334286003 hasConceptScore W2334286003C178790620 @default.
• W2334286003 hasConceptScore W2334286003C181199279 @default.
• W2334286003 hasConceptScore W2334286003C185592680 @default.
• W2334286003 hasConceptScore W2334286003C188027245 @default.
• W2334286003 hasConceptScore W2334286003C192562407 @default.
• W2334286003 hasConceptScore W2334286003C193363816 @default.
• W2334286003 hasConceptScore W2334286003C2775952280 @default.
• W2334286003 hasConceptScore W2334286003C2779769944 @default.
• W2334286003 hasConceptScore W2334286003C2780471494 @default.
• W2334286003 hasConceptScore W2334286003C33923547 @default.
• W2334286003 hasConceptScore W2334286003C43617362 @default.
• W2334286003 hasConceptScore W2334286003C44228677 @default.
• W2334286003 hasConceptScore W2334286003C521977710 @default.
• W2334286003 hasLocation W23342860031 @default.
• W2334286003 hasOpenAccess W2334286003 @default.
• W2334286003 hasPrimaryLocation W23342860031 @default.
• W2334286003 hasRelatedWork W2063484253 @default.
• W2334286003 hasRelatedWork W2085564457 @default.
• W2334286003 hasRelatedWork W2268280310 @default.
• W2334286003 hasRelatedWork W2368374654 @default.
• W2334286003 hasRelatedWork W2384023967 @default.
• W2334286003 hasRelatedWork W2389461698 @default.
• W2334286003 hasRelatedWork W2790648773 @default.
• W2334286003 hasRelatedWork W2919734648 @default.
• W2334286003 hasRelatedWork W2953275968 @default.
• W2334286003 hasRelatedWork W2673690726 @default.
• W2334286003 hasVolume "4" @default.
• W2334286003 isParatext "false" @default.
• W2334286003 isRetracted "false" @default.
• W2334286003 magId "2334286003" @default.
• W2334286003 workType "article" @default.