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- W2334332387 abstract "Repaglinide is an anti-diabetic drug used extensively in the treatment of diabetes type II. The present study was carried out to formulate and evaluate biphasic floating mini tablets of Repaglinide. These mini tablets were encapsulated in a capsule. Immediate release mini tablet (IRMT) were manufactured by direct compression using various superdisintegrating agents, each mini tablet containing 2mg Repaglinide. Sustained release mini tablet (SRMT) were formulated using various polymers, each mini tablet containing 4mg Repaglinide. The prepared mini tablets were subjected to pre and post compressional parameters and the values were within the prescribed limits. The drug- excipient compatibility studies were performed using FTIR techniques. The invitro performance showed the desired biphasic behaviour. Capsules were filled with individual mini tablets to deliver 6mg of Repaglinide designed to provide a multi particulate delivery of drug as immediate and sustained dissolution release profiles." @default.
- W2334332387 created "2016-06-24" @default.
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- W2334332387 date "2014-01-01" @default.
- W2334332387 modified "2023-09-27" @default.
- W2334332387 title "Formulation And Evaluation Of Repaglinide Biphasic Mini Tablets" @default.
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- W2334332387 doi "https://doi.org/10.9790/3008-09126673" @default.
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