Matches in SemOpenAlex for { <https://semopenalex.org/work/W2334381443> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2334381443 endingPage "267" @default.
- W2334381443 startingPage "260" @default.
- W2334381443 abstract "Allergic rhinitis caused by birch pollen is common in parts of Northern Europe, North America and the northern Japanese island of Hokkaido. The major antigenic fragment of European birch (Betula verrucosa) pollen allergen with a M. W. of 17k dalton was isolated and termed Bet vI. The amino acid sequence of Bet vI has already been identified. We have attempted to identify an antigenic peptide of Japanese birch (Betula platyphylla var. Japonica) pollen allergen. Seventeen Kd fragments separated from pollen allergen by SDS-PAGE were shown to bind with IgE in the pooled sera of pollinosis patients. The fragment was digested with trypsin and fractionated by reverse phase HPLC. Five fractions were identified to have in vitro activities, such as the lymphocyte proliferative response, in pollinosis patients. Amino acid sequences of peptides in the fractions were determined. The sequence of a 12-mer peptide was shown to correspond to that of No 22-33 of Bet vI, except for the amino acid at the 31st position, phenylalanine, which was instead isoleucine. Synthetic peptides based on this sequencing were shown to cause proliferation of lymphocytes, derived from pollinosis patients, which was blocked by monoclonal antibodies to HLA-DR molecules." @default.
- W2334381443 created "2016-06-24" @default.
- W2334381443 creator A5001841015 @default.
- W2334381443 creator A5009368549 @default.
- W2334381443 date "1994-01-01" @default.
- W2334381443 modified "2023-09-30" @default.
- W2334381443 title "Analysis of Antigenic Peptides Obtained from Japanese Birch Pollen." @default.
- W2334381443 cites W153972386 @default.
- W2334381443 cites W1932052686 @default.
- W2334381443 cites W1974061274 @default.
- W2334381443 cites W1999811293 @default.
- W2334381443 cites W2004327315 @default.
- W2334381443 cites W2008921531 @default.
- W2334381443 cites W2036794046 @default.
- W2334381443 cites W2040294304 @default.
- W2334381443 cites W2042811323 @default.
- W2334381443 cites W2044813843 @default.
- W2334381443 cites W2074072194 @default.
- W2334381443 cites W2084636378 @default.
- W2334381443 cites W2089339054 @default.
- W2334381443 cites W2093026457 @default.
- W2334381443 cites W2094814963 @default.
- W2334381443 cites W2103903862 @default.
- W2334381443 cites W2103963042 @default.
- W2334381443 cites W2470176651 @default.
- W2334381443 doi "https://doi.org/10.3950/jibiinkoka.97.260" @default.
- W2334381443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8169732" @default.
- W2334381443 hasPublicationYear "1994" @default.
- W2334381443 type Work @default.
- W2334381443 sameAs 2334381443 @default.
- W2334381443 citedByCount "2" @default.
- W2334381443 crossrefType "journal-article" @default.
- W2334381443 hasAuthorship W2334381443A5001841015 @default.
- W2334381443 hasAuthorship W2334381443A5009368549 @default.
- W2334381443 hasBestOaLocation W23343814431 @default.
- W2334381443 hasConcept C104317684 @default.
- W2334381443 hasConcept C147483822 @default.
- W2334381443 hasConcept C153911025 @default.
- W2334381443 hasConcept C167625842 @default.
- W2334381443 hasConcept C185592680 @default.
- W2334381443 hasConcept C203014093 @default.
- W2334381443 hasConcept C207480886 @default.
- W2334381443 hasConcept C2779281246 @default.
- W2334381443 hasConcept C2780510475 @default.
- W2334381443 hasConcept C2780618852 @default.
- W2334381443 hasConcept C2909083263 @default.
- W2334381443 hasConcept C55493867 @default.
- W2334381443 hasConcept C59822182 @default.
- W2334381443 hasConcept C86803240 @default.
- W2334381443 hasConceptScore W2334381443C104317684 @default.
- W2334381443 hasConceptScore W2334381443C147483822 @default.
- W2334381443 hasConceptScore W2334381443C153911025 @default.
- W2334381443 hasConceptScore W2334381443C167625842 @default.
- W2334381443 hasConceptScore W2334381443C185592680 @default.
- W2334381443 hasConceptScore W2334381443C203014093 @default.
- W2334381443 hasConceptScore W2334381443C207480886 @default.
- W2334381443 hasConceptScore W2334381443C2779281246 @default.
- W2334381443 hasConceptScore W2334381443C2780510475 @default.
- W2334381443 hasConceptScore W2334381443C2780618852 @default.
- W2334381443 hasConceptScore W2334381443C2909083263 @default.
- W2334381443 hasConceptScore W2334381443C55493867 @default.
- W2334381443 hasConceptScore W2334381443C59822182 @default.
- W2334381443 hasConceptScore W2334381443C86803240 @default.
- W2334381443 hasIssue "2" @default.
- W2334381443 hasLocation W23343814431 @default.
- W2334381443 hasLocation W23343814432 @default.
- W2334381443 hasOpenAccess W2334381443 @default.
- W2334381443 hasPrimaryLocation W23343814431 @default.
- W2334381443 hasRelatedWork W1988952014 @default.
- W2334381443 hasRelatedWork W199370328 @default.
- W2334381443 hasRelatedWork W2005085737 @default.
- W2334381443 hasRelatedWork W2044540551 @default.
- W2334381443 hasRelatedWork W2074501933 @default.
- W2334381443 hasRelatedWork W2120609186 @default.
- W2334381443 hasRelatedWork W2151592775 @default.
- W2334381443 hasRelatedWork W2334381443 @default.
- W2334381443 hasRelatedWork W2407548252 @default.
- W2334381443 hasRelatedWork W59895963 @default.
- W2334381443 hasVolume "97" @default.
- W2334381443 isParatext "false" @default.
- W2334381443 isRetracted "false" @default.
- W2334381443 magId "2334381443" @default.
- W2334381443 workType "article" @default.