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• W2334458061 abstract "Glucagon-like peptide-1 (GLP-1) is a potent antihyperglycemic hormone. It can induce glucose-dependent insulin secretion. GLP-1 has a short half-life of less than 2 min in vivo due to degradation by the dipeptidyl peptidase-IV. GLP-l analogues, such as exendin-4 and exendin-3, have similar biological activity but a longer in-vivo half-life. Pancreatic β-cells and pancreatic islet cell tumors highly express GLP-1 receptors. Hence, radiolabeled GLP-1 analogues play a potential role in imaging and radiation therapy of pancreatic islet cell tumors as well as in the monitoring of pancreatic β-cell transplantation." @default.
• W2334458061 created "2016-06-24" @default.
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• W2334458061 date "2012-03-01" @default.
• W2334458061 modified "2023-10-01" @default.
• W2334458061 title "Radiolabeled glucagon-like peptide-1 analogues" @default.
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• W2334458061 doi "https://doi.org/10.1097/mnm.0b013e32834e7f47" @default.
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