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• W2334507777 abstract "Recently, there has been a strong interest in the ability to increase levels of high density lipoprotein-cholesterol (HDL-C). This interest stems from the hypothesis that such an elevation in HDL-C will decrease the likelihood of cardiovascular disease. Inhibition of cholesteryl ester transfer protein (CETP) has been shown to elevate HDL-C levels in human subjects. This letter describes the discovery of a novel and potent (<100 nM IC50 for the inhibition of CE transfer) CETP inhibitor scaffold containing an oxazolidinone core." @default.
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• W2334507777 date "2011-03-31" @default.
• W2334507777 modified "2023-10-12" @default.
• W2334507777 title "Discovery of Substituted Biphenyl Oxazolidinone Inhibitors of Cholesteryl Ester Transfer Protein" @default.
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• W2334507777 doi "https://doi.org/10.1021/ml100309n" @default.
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