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- W2334631231 abstract "The purpose of this study was to examine the effect of sodium fluoride in combination with pyridoxine hydrochloride solution on artificial caries lesion formation. Human enamel blocks were immersed and stirred in three kinds of solution at 37°C for 1 hour. The three solutions were as follows: (1) sodium fluoride in combination with pyridoxine hydrochloride solution, 900ppm of fluoride (F-), pH 4.5-NaF+VB6 group; (2) hydrochloric acid-acidified sodium fluoride solution, 900ppm of fluoride (F-), pH 4.5-NaF group; and (3) de-ionized water-control group. Artificial caries lesions were formed with demineralizing solution according to Moreno (1974), consisting of 50% hydroxyapatite saturated lactate buffer (pH4.5). Morphological examinations and microbeam X-ray diffractometry were performed.In SEM preparations, a large amonut of spherical crystals were deposited on the enamel surface after fluoride treatment. In the NaF+VB6 group, these deposits were thicker and the crystals were larger than in the NaF group. No crystals were found in the control group. Calcium fluoride was detected on microbeam X-ray diffraction patterns of fluoride-treated enamel surface. The intensity of the X-ray diffraction pattern of calcium fluoride was highest in the NaF+VB6 group.After lesion formation, granular or needle-like deposits were observed on the lesion surface in the NaF+VB6 group. This surface was smoother than in the control group, and demineralized surfaces were observed in the NaF group. The caries lesions of the control and NaF groups showed clear subsurface demineralization in contact microradiograms and polarized light microscopy. In the NaF+VB6 group, the lesions were unclear and thinner than in the other two groups. The depth of caries lesions was about 33 μm in the NaF+VB6 group, and about 100μm in the NaF and control groups. This depth was estimated by doing an EPMA analysis of SEM photographs of cross sections of the lesions. The microbeam X-ray diffraction pattern of the caries lesions showed hydroxyapatite in all groups. In the fluoride groups, the crystallinity of the lesions was higher than in the control group, and was the same as that of sound enamel.These findings suggest that enamel immersed in sodium fluoride in combination with pyridoxine hydrochroride solution could be protected from artificial caries lesion formation." @default.
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- W2334631231 date "1993-01-01" @default.
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- W2334631231 title "Effect of Sodium Fluoride in Combination with Pyridoxine Hydrochloride on the Artificial Caries Lesion Formation." @default.
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- W2334631231 doi "https://doi.org/10.5834/jdh.43.681" @default.
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