Matches in SemOpenAlex for { <https://semopenalex.org/work/W2334697258> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2334697258 endingPage "62" @default.
- W2334697258 startingPage "55" @default.
- W2334697258 abstract "14C-nizatidineを5mg/kgで雄性イヌに単回経口投与後の吸収，代謝および排泄について検討した．1．血液中放射能濃度は投与後1時間に最高値(1876ngeq./ml)を示したのち，12時間まで半減期2.05時間で消失した．2．投与後120時間までの尿中には投与量の88.4%，糞中には8.1%の放射能が排泄された．3．in vitroでの血漿蛋白結合率は0.1～10μg/mlの範囲でイヌでは11.0～18.6%，ヒトでは23.9～45.4%であった．投与後2，4および8時間でのイヌ血漿蛋白結合率は，それぞれ7.6，5.8および15.7%であった．4．投与後の血漿および尿中には未変化体，M-3およびS-oxide体が主として検出された．5．MSおよびNMRによりM-3はN-oxide体と同定された．" @default.
- W2334697258 created "2016-06-24" @default.
- W2334697258 creator A5024742540 @default.
- W2334697258 creator A5029243193 @default.
- W2334697258 creator A5044538377 @default.
- W2334697258 creator A5056265427 @default.
- W2334697258 creator A5062415535 @default.
- W2334697258 creator A5071354099 @default.
- W2334697258 creator A5076249681 @default.
- W2334697258 creator A5086987725 @default.
- W2334697258 creator A5037048113 @default.
- W2334697258 date "1989-01-01" @default.
- W2334697258 modified "2023-09-27" @default.
- W2334697258 title "Studies on the metabolic fate of nizatidine. (III). Absorption, metabolism and excretion in dogs." @default.
- W2334697258 cites W1841356388 @default.
- W2334697258 cites W2148224822 @default.
- W2334697258 doi "https://doi.org/10.2133/dmpk.4.55" @default.
- W2334697258 hasPublicationYear "1989" @default.
- W2334697258 type Work @default.
- W2334697258 sameAs 2334697258 @default.
- W2334697258 citedByCount "0" @default.
- W2334697258 crossrefType "journal-article" @default.
- W2334697258 hasAuthorship W2334697258A5024742540 @default.
- W2334697258 hasAuthorship W2334697258A5029243193 @default.
- W2334697258 hasAuthorship W2334697258A5037048113 @default.
- W2334697258 hasAuthorship W2334697258A5044538377 @default.
- W2334697258 hasAuthorship W2334697258A5056265427 @default.
- W2334697258 hasAuthorship W2334697258A5062415535 @default.
- W2334697258 hasAuthorship W2334697258A5071354099 @default.
- W2334697258 hasAuthorship W2334697258A5076249681 @default.
- W2334697258 hasAuthorship W2334697258A5086987725 @default.
- W2334697258 hasBestOaLocation W23346972581 @default.
- W2334697258 hasConcept C10146269 @default.
- W2334697258 hasConcept C125287762 @default.
- W2334697258 hasConcept C126322002 @default.
- W2334697258 hasConcept C159985019 @default.
- W2334697258 hasConcept C185592680 @default.
- W2334697258 hasConcept C192562407 @default.
- W2334697258 hasConcept C55493867 @default.
- W2334697258 hasConcept C62231903 @default.
- W2334697258 hasConcept C71924100 @default.
- W2334697258 hasConcept C98274493 @default.
- W2334697258 hasConceptScore W2334697258C10146269 @default.
- W2334697258 hasConceptScore W2334697258C125287762 @default.
- W2334697258 hasConceptScore W2334697258C126322002 @default.
- W2334697258 hasConceptScore W2334697258C159985019 @default.
- W2334697258 hasConceptScore W2334697258C185592680 @default.
- W2334697258 hasConceptScore W2334697258C192562407 @default.
- W2334697258 hasConceptScore W2334697258C55493867 @default.
- W2334697258 hasConceptScore W2334697258C62231903 @default.
- W2334697258 hasConceptScore W2334697258C71924100 @default.
- W2334697258 hasConceptScore W2334697258C98274493 @default.
- W2334697258 hasIssue "1" @default.
- W2334697258 hasLocation W23346972581 @default.
- W2334697258 hasOpenAccess W2334697258 @default.
- W2334697258 hasPrimaryLocation W23346972581 @default.
- W2334697258 hasRelatedWork W1978816258 @default.
- W2334697258 hasRelatedWork W2059373368 @default.
- W2334697258 hasRelatedWork W2323228041 @default.
- W2334697258 hasRelatedWork W2414115837 @default.
- W2334697258 hasRelatedWork W2415729534 @default.
- W2334697258 hasRelatedWork W2418058725 @default.
- W2334697258 hasRelatedWork W2523143010 @default.
- W2334697258 hasRelatedWork W2748952813 @default.
- W2334697258 hasRelatedWork W2899084033 @default.
- W2334697258 hasRelatedWork W279462874 @default.
- W2334697258 hasVolume "4" @default.
- W2334697258 isParatext "false" @default.
- W2334697258 isRetracted "false" @default.
- W2334697258 magId "2334697258" @default.
- W2334697258 workType "article" @default.