Matches in SemOpenAlex for { <https://semopenalex.org/work/W2334710105> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2334710105 abstract "A new high performance liquid chromatographic (HPLC) method with column switching was developed for quantitative analysis of the new antipsychotic drug ziprasidone in serum. On-line sample clean-up was conducted on silica C8 material (20µm particle size). The drug was separated on ODS Hypersil C18 material (5µm; column size 250×4.6mm I. D.) within 20min. The limit of quantification was 10 ng/ml. At therapeutic concentrations of the drug, the inter-assay reproducibility (coefficients of variation) of quality control samples was below 10%. The application of the method on serum of 41 patients treated with ziprasidone (mean±SD dose 117±47mg/day) revealed serum concentrations between 5 and 424 ng/ml (mean±SD, 71±75 ng/ml, median 52 ng/ml, 25th and 75th percentile 31 to 81 ng/ml, respectively. This new method is suitable for TDM and pharmacokinetic studies of ziprasidone." @default.
- W2334710105 created "2016-06-24" @default.
- W2334710105 creator A5007740742 @default.
- W2334710105 creator A5051832248 @default.
- W2334710105 creator A5060828836 @default.
- W2334710105 creator A5081339058 @default.
- W2334710105 date "2004-06-09" @default.
- W2334710105 modified "2023-09-25" @default.
- W2334710105 title "Therapeutic drug monitoring of ziprasidone" @default.
- W2334710105 doi "https://doi.org/10.1055/s-2003-825484" @default.
- W2334710105 hasPublicationYear "2004" @default.
- W2334710105 type Work @default.
- W2334710105 sameAs 2334710105 @default.
- W2334710105 citedByCount "0" @default.
- W2334710105 crossrefType "journal-article" @default.
- W2334710105 hasAuthorship W2334710105A5007740742 @default.
- W2334710105 hasAuthorship W2334710105A5051832248 @default.
- W2334710105 hasAuthorship W2334710105A5060828836 @default.
- W2334710105 hasAuthorship W2334710105A5081339058 @default.
- W2334710105 hasConcept C112705442 @default.
- W2334710105 hasConcept C118552586 @default.
- W2334710105 hasConcept C119128265 @default.
- W2334710105 hasConcept C185592680 @default.
- W2334710105 hasConcept C2776412080 @default.
- W2334710105 hasConcept C2777270317 @default.
- W2334710105 hasConcept C2780035454 @default.
- W2334710105 hasConcept C2780272996 @default.
- W2334710105 hasConcept C2780494398 @default.
- W2334710105 hasConcept C43617362 @default.
- W2334710105 hasConcept C71924100 @default.
- W2334710105 hasConcept C98274493 @default.
- W2334710105 hasConcept C9893847 @default.
- W2334710105 hasConceptScore W2334710105C112705442 @default.
- W2334710105 hasConceptScore W2334710105C118552586 @default.
- W2334710105 hasConceptScore W2334710105C119128265 @default.
- W2334710105 hasConceptScore W2334710105C185592680 @default.
- W2334710105 hasConceptScore W2334710105C2776412080 @default.
- W2334710105 hasConceptScore W2334710105C2777270317 @default.
- W2334710105 hasConceptScore W2334710105C2780035454 @default.
- W2334710105 hasConceptScore W2334710105C2780272996 @default.
- W2334710105 hasConceptScore W2334710105C2780494398 @default.
- W2334710105 hasConceptScore W2334710105C43617362 @default.
- W2334710105 hasConceptScore W2334710105C71924100 @default.
- W2334710105 hasConceptScore W2334710105C98274493 @default.
- W2334710105 hasConceptScore W2334710105C9893847 @default.
- W2334710105 hasIssue "05" @default.
- W2334710105 hasLocation W23347101051 @default.
- W2334710105 hasOpenAccess W2334710105 @default.
- W2334710105 hasPrimaryLocation W23347101051 @default.
- W2334710105 hasRelatedWork W1969876219 @default.
- W2334710105 hasRelatedWork W2011472641 @default.
- W2334710105 hasRelatedWork W2023350722 @default.
- W2334710105 hasRelatedWork W2049819497 @default.
- W2334710105 hasRelatedWork W2064784853 @default.
- W2334710105 hasRelatedWork W2400461952 @default.
- W2334710105 hasRelatedWork W2414126392 @default.
- W2334710105 hasRelatedWork W2420918848 @default.
- W2334710105 hasRelatedWork W2567767604 @default.
- W2334710105 hasRelatedWork W4205993769 @default.
- W2334710105 hasVolume "36" @default.
- W2334710105 isParatext "false" @default.
- W2334710105 isRetracted "false" @default.
- W2334710105 magId "2334710105" @default.
- W2334710105 workType "article" @default.