Matches in SemOpenAlex for { <https://semopenalex.org/work/W2334851730> ?p ?o ?g. }
- W2334851730 abstract "Heme oxygenase (HO), the rate-limiting enzyme in heme degradation, and its byproducts have antioxidative, antiapoptotic, anti-inflammatory, and cytoprotective properties. The expression of the inducible isoform, HO-1, in various tissues is increased in newborns, decreases toward adulthood, and may be of pivotal importance during the perinatal period. During pregnancy, it may mediate the regulation of maternal blood pressure, placental development, and vascularization, and, therefore, the maintenance of a healthy pregnancy. Pregnancy disorders, such as intrauterine growth restriction and preeclampsia, contribute significantly to preterm births as well as to perinatal morbidity and mortality and manifest even into adulthood. They stem from placental defects mediated by fetal genetic defects, maternal factors, or both. HO-1 has been shown to play a role in the maintenance of maternal inflammatory homeostasis and normal placental vasculature development by regulating angiogenesis and matrix remodeling in early pregnancy. Therefore, a genetic deficiency in HO-1 gene expression may be an underlying cause of pregnancy disorders, in particular, those attributed to placental dysfunction." @default.
- W2334851730 created "2016-06-24" @default.
- W2334851730 creator A5008116183 @default.
- W2334851730 creator A5036674274 @default.
- W2334851730 creator A5055733234 @default.
- W2334851730 creator A5063792544 @default.
- W2334851730 date "2012-03-01" @default.
- W2334851730 modified "2023-09-22" @default.
- W2334851730 title "Heme Oxygenase Biology (During the Perinatal Period): Part 1: Prenatal Considerations" @default.
- W2334851730 cites W1600690434 @default.
- W2334851730 cites W165152900 @default.
- W2334851730 cites W1965612716 @default.
- W2334851730 cites W1966582616 @default.
- W2334851730 cites W1973081785 @default.
- W2334851730 cites W1978314464 @default.
- W2334851730 cites W1979464484 @default.
- W2334851730 cites W1981428946 @default.
- W2334851730 cites W1984970610 @default.
- W2334851730 cites W1992571487 @default.
- W2334851730 cites W1997989985 @default.
- W2334851730 cites W2001003675 @default.
- W2334851730 cites W2001019228 @default.
- W2334851730 cites W2003664528 @default.
- W2334851730 cites W2005904261 @default.
- W2334851730 cites W2009137800 @default.
- W2334851730 cites W2014067471 @default.
- W2334851730 cites W2017353776 @default.
- W2334851730 cites W2028778467 @default.
- W2334851730 cites W2035718092 @default.
- W2334851730 cites W2040278821 @default.
- W2334851730 cites W2043206459 @default.
- W2334851730 cites W2053976090 @default.
- W2334851730 cites W2056523101 @default.
- W2334851730 cites W2057770637 @default.
- W2334851730 cites W2058993916 @default.
- W2334851730 cites W2059054070 @default.
- W2334851730 cites W2066033513 @default.
- W2334851730 cites W2066783947 @default.
- W2334851730 cites W2068155900 @default.
- W2334851730 cites W2074818111 @default.
- W2334851730 cites W2081546649 @default.
- W2334851730 cites W2093772580 @default.
- W2334851730 cites W2098209538 @default.
- W2334851730 cites W2111496692 @default.
- W2334851730 cites W2120505405 @default.
- W2334851730 cites W2125395056 @default.
- W2334851730 cites W2129206669 @default.
- W2334851730 cites W2139248955 @default.
- W2334851730 cites W2142060219 @default.
- W2334851730 cites W2150153026 @default.
- W2334851730 cites W2161262137 @default.
- W2334851730 cites W2166803343 @default.
- W2334851730 cites W2081255404 @default.
- W2334851730 doi "https://doi.org/10.1542/neo.13-3-e151" @default.
- W2334851730 hasPublicationYear "2012" @default.
- W2334851730 type Work @default.
- W2334851730 sameAs 2334851730 @default.
- W2334851730 citedByCount "1" @default.
- W2334851730 countsByYear W23348517302013 @default.
- W2334851730 crossrefType "journal-article" @default.
- W2334851730 hasAuthorship W2334851730A5008116183 @default.
- W2334851730 hasAuthorship W2334851730A5036674274 @default.
- W2334851730 hasAuthorship W2334851730A5055733234 @default.
- W2334851730 hasAuthorship W2334851730A5063792544 @default.
- W2334851730 hasConcept C126322002 @default.
- W2334851730 hasConcept C134018914 @default.
- W2334851730 hasConcept C172680121 @default.
- W2334851730 hasConcept C181199279 @default.
- W2334851730 hasConcept C2776217839 @default.
- W2334851730 hasConcept C2776847746 @default.
- W2334851730 hasConcept C2776953305 @default.
- W2334851730 hasConcept C2777218350 @default.
- W2334851730 hasConcept C2778780700 @default.
- W2334851730 hasConcept C2779219270 @default.
- W2334851730 hasConcept C2779234561 @default.
- W2334851730 hasConcept C2780394083 @default.
- W2334851730 hasConcept C42407357 @default.
- W2334851730 hasConcept C54355233 @default.
- W2334851730 hasConcept C55493867 @default.
- W2334851730 hasConcept C63645605 @default.
- W2334851730 hasConcept C71924100 @default.
- W2334851730 hasConcept C86803240 @default.
- W2334851730 hasConceptScore W2334851730C126322002 @default.
- W2334851730 hasConceptScore W2334851730C134018914 @default.
- W2334851730 hasConceptScore W2334851730C172680121 @default.
- W2334851730 hasConceptScore W2334851730C181199279 @default.
- W2334851730 hasConceptScore W2334851730C2776217839 @default.
- W2334851730 hasConceptScore W2334851730C2776847746 @default.
- W2334851730 hasConceptScore W2334851730C2776953305 @default.
- W2334851730 hasConceptScore W2334851730C2777218350 @default.
- W2334851730 hasConceptScore W2334851730C2778780700 @default.
- W2334851730 hasConceptScore W2334851730C2779219270 @default.
- W2334851730 hasConceptScore W2334851730C2779234561 @default.
- W2334851730 hasConceptScore W2334851730C2780394083 @default.
- W2334851730 hasConceptScore W2334851730C42407357 @default.
- W2334851730 hasConceptScore W2334851730C54355233 @default.
- W2334851730 hasConceptScore W2334851730C55493867 @default.
- W2334851730 hasConceptScore W2334851730C63645605 @default.
- W2334851730 hasConceptScore W2334851730C71924100 @default.
- W2334851730 hasConceptScore W2334851730C86803240 @default.