FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2334854050> ?p ?o ?g. }

• W2334854050 endingPage "182" @default.
• W2334854050 startingPage "175" @default.
• W2334854050 abstract "Objective We analyzed renal kinetics and renal oxygenation in rats after administration of several classes and formulations of contrast agents (CAs) with a focus on the influence of osmolality and substance-specific properties. Materials and Methods We investigated the renal kinetics of a nonionic, dimeric CA (iodixanol) formulated in 3 different osmolalities (hypo-osmolar, iso-osmolar, low-osmolar) and compared it to nonionic, low-osmolar (iopromide), and ionic, low-osmolar CAs (ioxaglate) using computed tomography for a period of 24 hours. The CAs were administered intravenously at a dosage of 4 g iodine/kg body weight. The average exposure was calculated, and urine viscosities were compared before the injection and during the time intervals of 0 to 60 minutes and 60 to 120 minutes after the injection. Renal oxygenation levels of the renal cortex and medulla were estimated using blood-oxygen-level–dependent magnetic resonance imaging. We used histologic methods to systematically analyze the gravity of vacuole formation based on the physicochemical and substance-specific properties of each CA. Results Iso-osmolar and hypo-osmolar iodixanol and, to a lesser extent, iodixanol/mannitol accumulated rapidly in the kidneys during the first 5 minutes of the injection and remained higher 2, 4, 6, and 24 hours after the injection compared with iopromide and ioxaglate, which showed fast iodine excretion. Similarly, lower renal blood oxygen levels were estimated for all iodixanol formulations as compared with ioxaglate and iopromide. The incidence of vacuole formation was high for all iodixanol formulations and for ioxaglate (6 of 6 rats) and low for iopromide (1 of 6 rats). Moderate severity of vacuoles was determined for the iodixanol solutions; minimal severity, for ioxaglate and iopromide. Conclusions We identified a superior profile for the low-osmolar CAs compared with the iso-osmolar CAs regarding rapid excretion, short-term renal exposure, and renal oxygenation." @default.
• W2334854050 created "2016-06-24" @default.
• W2334854050 creator A5013615102 @default.
• W2334854050 creator A5020975288 @default.
• W2334854050 creator A5041996439 @default.
• W2334854050 creator A5067957981 @default.
• W2334854050 creator A5074900490 @default.
• W2334854050 date "2013-04-01" @default.
• W2334854050 modified "2023-09-27" @default.
• W2334854050 title "The Effect of Iodinated Contrast Agent Properties on Renal Kinetics and Oxygenation" @default.
• W2334854050 cites W1555034762 @default.
• W2334854050 cites W1577820753 @default.
• W2334854050 cites W1964144500 @default.
• W2334854050 cites W1968698443 @default.
• W2334854050 cites W1970753596 @default.
• W2334854050 cites W1971038471 @default.
• W2334854050 cites W1974191809 @default.
• W2334854050 cites W1980489046 @default.
• W2334854050 cites W1983186817 @default.
• W2334854050 cites W1983714823 @default.
• W2334854050 cites W1999584733 @default.
• W2334854050 cites W2000158535 @default.
• W2334854050 cites W2011058508 @default.
• W2334854050 cites W2018669448 @default.
• W2334854050 cites W2024504959 @default.
• W2334854050 cites W2026051108 @default.
• W2334854050 cites W2032600130 @default.
• W2334854050 cites W2033982773 @default.
• W2334854050 cites W2037526692 @default.
• W2334854050 cites W2041735436 @default.
• W2334854050 cites W2047859294 @default.
• W2334854050 cites W2048212167 @default.
• W2334854050 cites W2051841236 @default.
• W2334854050 cites W2061514693 @default.
• W2334854050 cites W2061859436 @default.
• W2334854050 cites W2063971310 @default.
• W2334854050 cites W2073732531 @default.
• W2334854050 cites W2075412580 @default.
• W2334854050 cites W2087870652 @default.
• W2334854050 cites W2092783802 @default.
• W2334854050 cites W2100620904 @default.
• W2334854050 cites W2130865312 @default.
• W2334854050 cites W2132347872 @default.
• W2334854050 cites W2133303352 @default.
• W2334854050 cites W2136860319 @default.
• W2334854050 cites W2145685319 @default.
• W2334854050 cites W2153104532 @default.
• W2334854050 cites W2319164492 @default.
• W2334854050 cites W2326147148 @default.
• W2334854050 cites W2328369969 @default.
• W2334854050 cites W4246848668 @default.
• W2334854050 doi "https://doi.org/10.1097/rli.0b013e31827b70f9" @default.
• W2334854050 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23262792" @default.
• W2334854050 hasPublicationYear "2013" @default.
• W2334854050 type Work @default.
• W2334854050 sameAs 2334854050 @default.
• W2334854050 citedByCount "27" @default.
• W2334854050 countsByYear W23348540502013 @default.
• W2334854050 countsByYear W23348540502014 @default.
• W2334854050 countsByYear W23348540502015 @default.
• W2334854050 countsByYear W23348540502016 @default.
• W2334854050 countsByYear W23348540502017 @default.
• W2334854050 countsByYear W23348540502018 @default.
• W2334854050 countsByYear W23348540502019 @default.
• W2334854050 countsByYear W23348540502020 @default.
• W2334854050 countsByYear W23348540502021 @default.
• W2334854050 countsByYear W23348540502022 @default.
• W2334854050 countsByYear W23348540502023 @default.
• W2334854050 crossrefType "journal-article" @default.
• W2334854050 hasAuthorship W2334854050A5013615102 @default.
• W2334854050 hasAuthorship W2334854050A5020975288 @default.
• W2334854050 hasAuthorship W2334854050A5041996439 @default.
• W2334854050 hasAuthorship W2334854050A5067957981 @default.
• W2334854050 hasAuthorship W2334854050A5074900490 @default.
• W2334854050 hasConcept C10146269 @default.
• W2334854050 hasConcept C126322002 @default.
• W2334854050 hasConcept C126838900 @default.
• W2334854050 hasConcept C126894567 @default.
• W2334854050 hasConcept C159641895 @default.
• W2334854050 hasConcept C178790620 @default.
• W2334854050 hasConcept C185592680 @default.
• W2334854050 hasConcept C2776982972 @default.
• W2334854050 hasConcept C2778577996 @default.
• W2334854050 hasConcept C2778754328 @default.
• W2334854050 hasConcept C2779093167 @default.
• W2334854050 hasConcept C2779222893 @default.
• W2334854050 hasConcept C2779786684 @default.
• W2334854050 hasConcept C2780091579 @default.
• W2334854050 hasConcept C2780512574 @default.
• W2334854050 hasConcept C2780929046 @default.
• W2334854050 hasConcept C2989005 @default.
• W2334854050 hasConcept C539932907 @default.
• W2334854050 hasConcept C544519230 @default.
• W2334854050 hasConcept C70289976 @default.
• W2334854050 hasConcept C71924100 @default.
• W2334854050 hasConcept C98274493 @default.
• W2334854050 hasConceptScore W2334854050C10146269 @default.
• W2334854050 hasConceptScore W2334854050C126322002 @default.

• next