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- W2334874736 abstract "Cryptosporidisis parvum is a zoonotic protozoan parasite infects intestinal epithelial cells causing a major health problem for man and animals. Experimentally the immunologic mediated elimination of C. parvum requires CD4+ T cells and IFN-gamma. But, the innate immune responses also have a significant protective role in both man and animals. the mucosal immune response to C. parvum in C57BL/6 neonatal and GKO mice shows a concomitant Thl and Th2 cytokine mRNA expression, with a crucial role for IFN-gamma in the resolution of the infection. NK cells and IFN-gamma have been shown to be important components in immunity in T and B cell-deficient mice, but IFN-gamma-dependent resistance is demonstrated in alymphocytic mice. Epithelial cells may play a vital role in immunity as once infected these cells have increased expression of inflammatory chemokines and cytokines and demonstrate anti-infection killing mechanisms. C. parvum immunological response was used to evaluate the efficacy of anti-cryptosporidisis agents of Garlic, Ginger, Mirazid and Metronidazole in experimentally infected mice." @default.
- W2334874736 created "2016-06-24" @default.
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- W2334874736 date "2015-12-01" @default.
- W2334874736 modified "2023-10-16" @default.
- W2334874736 title "The Efficacy of Three Medicinal Plants : Garlic , Ginger and Mirazid and a Chemical Drug Metronidazole against Cryptosporidium Parvum. I-Immunological Response" @default.
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- W2334874736 doi "https://doi.org/10.12816/0017916" @default.
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