FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2334883358> ?p ?o ?g. }

• W2334883358 endingPage "1582" @default.
• W2334883358 startingPage "1575" @default.
• W2334883358 abstract "<h3>Objective</h3> Yes-associated protein (YAP) was defined as a candidate oncogene in multiple cancers. Yet, the role of YAP in cervical cancer is largely unknown. The aim of this study was to determine whether YAP could be used as a predictive biomarker in cervical precancerous lesions. <h3>Methods</h3> Immunohistochemical analysis of YAP expression was performed in 10 chronic cervicitis, 49 cervical intraepithelial neoplasia (CIN) 1, 55 CIN 2, 34 CIN 3, and 32 cervical squamous cell carcinoma (SCC) samples. Human papillomavirus (HPV) was detected by HPV genotype detection kit in 70 cases including 10 chronic cervicitis cases, 13 CIN 1 cases, 19 CIN 2 cases, 14 CIN 3 cases, and 14 SCC cases. Furthermore, the relationship between YAP expression and HPV integration status was analyzed using Spearman rank correlation coefficient test. <h3>Result</h3> Samples of chronic cervicitis had negative or weak expression of YAP in cytoplasm. In the CIN 1 group, YAP expression was primarily confined to the lower third part of squamous epithelia or basal layer, whereas higher-grade CIN (2 and 3) and SCC groups had a strong nuclear expression of YAP. The expression levels of YAP in chronic cervicitis and CIN 1 were significantly lower compared to those in higher-grade CIN and SCC. Moreover, YAP expression was correlated with HPV integration status. Most high-risk HPV(+)/YAP(+) cases were found in the CIN 3 and SCC groups. <h3>Conclusion</h3> This study suggested that YAP could function as a predictive marker in CIN and cervical cancer. YAP expression, in combination of HPV, might facilitate the identification of precancerous cervical lesions." @default.
• W2334883358 created "2016-06-24" @default.
• W2334883358 creator A5006219539 @default.
• W2334883358 creator A5031810848 @default.
• W2334883358 creator A5038449259 @default.
• W2334883358 creator A5038656025 @default.
• W2334883358 creator A5048981672 @default.
• W2334883358 creator A5062290295 @default.
• W2334883358 creator A5086662417 @default.
• W2334883358 creator A5091839496 @default.
• W2334883358 date "2014-11-01" @default.
• W2334883358 modified "2023-10-16" @default.
• W2334883358 title "Expression of Yes-Associated Protein in Cervical Squamous Epithelium Lesions" @default.
• W2334883358 cites W1964927845 @default.
• W2334883358 cites W1965696660 @default.
• W2334883358 cites W1968659021 @default.
• W2334883358 cites W1975284118 @default.
• W2334883358 cites W1980084312 @default.
• W2334883358 cites W1982953415 @default.
• W2334883358 cites W1983028616 @default.
• W2334883358 cites W1992294689 @default.
• W2334883358 cites W1998310906 @default.
• W2334883358 cites W1999404175 @default.
• W2334883358 cites W2003044806 @default.
• W2334883358 cites W2007079916 @default.
• W2334883358 cites W2011818472 @default.
• W2334883358 cites W2022423243 @default.
• W2334883358 cites W2029317188 @default.
• W2334883358 cites W2029608021 @default.
• W2334883358 cites W2034781859 @default.
• W2334883358 cites W2041862829 @default.
• W2334883358 cites W2049791689 @default.
• W2334883358 cites W2050552243 @default.
• W2334883358 cites W2062795871 @default.
• W2334883358 cites W2066834338 @default.
• W2334883358 cites W2076166544 @default.
• W2334883358 cites W2088578285 @default.
• W2334883358 cites W2099709490 @default.
• W2334883358 cites W2101538557 @default.
• W2334883358 cites W2121513122 @default.
• W2334883358 cites W2126655402 @default.
• W2334883358 cites W2131180223 @default.
• W2334883358 cites W2131255017 @default.
• W2334883358 cites W2132256680 @default.
• W2334883358 cites W2139736159 @default.
• W2334883358 cites W2141595533 @default.
• W2334883358 cites W2149354625 @default.
• W2334883358 cites W2156793931 @default.
• W2334883358 cites W2159376228 @default.
• W2334883358 cites W2166192753 @default.
• W2334883358 cites W2168733003 @default.
• W2334883358 cites W2174023915 @default.
• W2334883358 cites W4238398623 @default.
• W2334883358 cites W4253186498 @default.
• W2334883358 cites W4377996028 @default.
• W2334883358 cites W61968263 @default.
• W2334883358 doi "https://doi.org/10.1097/igc.0000000000000259" @default.
• W2334883358 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25304677" @default.
• W2334883358 hasPublicationYear "2014" @default.
• W2334883358 type Work @default.
• W2334883358 sameAs 2334883358 @default.
• W2334883358 citedByCount "24" @default.
• W2334883358 countsByYear W23348833582015 @default.
• W2334883358 countsByYear W23348833582016 @default.
• W2334883358 countsByYear W23348833582017 @default.
• W2334883358 countsByYear W23348833582018 @default.
• W2334883358 countsByYear W23348833582019 @default.
• W2334883358 countsByYear W23348833582020 @default.
• W2334883358 countsByYear W23348833582021 @default.
• W2334883358 countsByYear W23348833582022 @default.
• W2334883358 countsByYear W23348833582023 @default.
• W2334883358 crossrefType "journal-article" @default.
• W2334883358 hasAuthorship W2334883358A5006219539 @default.
• W2334883358 hasAuthorship W2334883358A5031810848 @default.
• W2334883358 hasAuthorship W2334883358A5038449259 @default.
• W2334883358 hasAuthorship W2334883358A5038656025 @default.
• W2334883358 hasAuthorship W2334883358A5048981672 @default.
• W2334883358 hasAuthorship W2334883358A5062290295 @default.
• W2334883358 hasAuthorship W2334883358A5086662417 @default.
• W2334883358 hasAuthorship W2334883358A5091839496 @default.
• W2334883358 hasConcept C121608353 @default.
• W2334883358 hasConcept C126322002 @default.
• W2334883358 hasConcept C138055712 @default.
• W2334883358 hasConcept C142724271 @default.
• W2334883358 hasConcept C143998085 @default.
• W2334883358 hasConcept C204232928 @default.
• W2334883358 hasConcept C2776185287 @default.
• W2334883358 hasConcept C2777343196 @default.
• W2334883358 hasConcept C2778220009 @default.
• W2334883358 hasConcept C2778580637 @default.
• W2334883358 hasConcept C2781018059 @default.
• W2334883358 hasConcept C29456083 @default.
• W2334883358 hasConcept C29537977 @default.
• W2334883358 hasConcept C529295009 @default.
• W2334883358 hasConcept C71924100 @default.
• W2334883358 hasConceptScore W2334883358C121608353 @default.
• W2334883358 hasConceptScore W2334883358C126322002 @default.
• W2334883358 hasConceptScore W2334883358C138055712 @default.

• next