FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2335020717> ?p ?o ?g. }

• W2335020717 endingPage "1005" @default.
• W2335020717 startingPage "997" @default.
• W2335020717 abstract "In Brief Objective: To evaluate the association of pretrauma center (PTC) red blood cell (RBC) transfusion with outcomes in severely injured patients. Background: Hemorrhage remains a major driver of mortality. Little evidence exists supporting PTC interventions to mitigate this. Methods: Blunt injured patients in shock arriving at a trauma center within 2 hours of injury were included from the Glue Grant database. Subjects were dichotomized by PTC RBC transfusion. Outcomes included 24-hour mortality, 30-day mortality, and trauma-induced coagulopathy [(TIC), admission international normalized ratio >1.5]. Cox regression and logistic regression determined the association of PTC RBC transfusion with outcomes. To address baseline differences, propensity score matching was used. Results: Of 1415 subjects, 50 received PTC RBC transfusion. Demographics and injury severity score were similar. The PTC RBC group received 1.3 units of RBCs (median), and 52% were scene transports. PTC RBC transfusion was associated with a 95% reduction in odds of 24-hour mortality [odds ratio (OR) = 0.05; 95% confidence interval (CI), 0.01–0.48; P < 0.01], 64% reduction in the risk of 30-day mortality [hazard ratio = 0.36; 95% CI, 0.15–0.83; P = 0.02], and 88% reduction in odds of TIC (OR = 0.12; 95% CI, 0.02–0.79; P = 0.03). The matched cohort included 113 subjects (31% PTC RBC group). Baseline characteristics were similar. PTC RBC transfusion was associated with a 98% reduction in odds of 24-hour mortality (OR = 0.02; 95% CI, 0.01–0.69; P = 0.04), 88% reduction in the risk of 30-day mortality (hazard ratio = 0.12; 95% CI, 0.03–0.61; P = 0.01), and 99% reduction in odds of TIC (OR = 0.01; 95% CI, 0.01–0.95; P = 0.05). Conclusions: PTC RBC administration was associated with a lower risk of 24-hour mortality, 30-day mortality, and TIC in severely injured patients with blunt trauma, warranting further prospective study. No prior studies have compared outcomes in patients receiving pretrauma center (PTC) red blood cell (RBC) transfusion for trauma. Regression and propensity score matching were used to evaluate outcomes in blunt injured patients undergoing PTC RBC transfusion. PTC RBC transfusion was associated with a reduced risk of 24-hour mortality, 30-day mortality, and coagulopathy, warranting further study." @default.
• W2335020717 created "2016-06-24" @default.
• W2335020717 creator A5012229337 @default.
• W2335020717 creator A5021897609 @default.
• W2335020717 creator A5028689777 @default.
• W2335020717 creator A5029774861 @default.
• W2335020717 creator A5041612225 @default.
• W2335020717 creator A5062076820 @default.
• W2335020717 creator A5063900162 @default.
• W2335020717 creator A5067313142 @default.
• W2335020717 creator A5073637013 @default.
• W2335020717 creator A5081036923 @default.
• W2335020717 date "2015-05-01" @default.
• W2335020717 modified "2023-10-06" @default.
• W2335020717 title "Pretrauma Center Red Blood Cell Transfusion Is Associated With Reduced Mortality and Coagulopathy in Severely Injured Patients With Blunt Trauma" @default.
• W2335020717 cites W1915228156 @default.
• W2335020717 cites W1964539910 @default.
• W2335020717 cites W1968335051 @default.
• W2335020717 cites W1969097686 @default.
• W2335020717 cites W1971267214 @default.
• W2335020717 cites W2003845570 @default.
• W2335020717 cites W2006959150 @default.
• W2335020717 cites W2012191523 @default.
• W2335020717 cites W2018007880 @default.
• W2335020717 cites W2024808820 @default.
• W2335020717 cites W2027232363 @default.
• W2335020717 cites W2032987611 @default.
• W2335020717 cites W2039446875 @default.
• W2335020717 cites W2057053578 @default.
• W2335020717 cites W2060930754 @default.
• W2335020717 cites W2061951538 @default.
• W2335020717 cites W2062829950 @default.
• W2335020717 cites W2063275011 @default.
• W2335020717 cites W2065191944 @default.
• W2335020717 cites W2069785744 @default.
• W2335020717 cites W2071582336 @default.
• W2335020717 cites W2077008458 @default.
• W2335020717 cites W2078929836 @default.
• W2335020717 cites W2083005745 @default.
• W2335020717 cites W2084280207 @default.
• W2335020717 cites W2091685079 @default.
• W2335020717 cites W2092787425 @default.
• W2335020717 cites W2113176369 @default.
• W2335020717 cites W2127379488 @default.
• W2335020717 cites W2128128223 @default.
• W2335020717 cites W2128719413 @default.
• W2335020717 cites W2132814098 @default.
• W2335020717 cites W2139223176 @default.
• W2335020717 cites W2150100219 @default.
• W2335020717 cites W2167490208 @default.
• W2335020717 cites W2180253585 @default.
• W2335020717 cites W2323966499 @default.
• W2335020717 doi "https://doi.org/10.1097/sla.0000000000000674" @default.
• W2335020717 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4176550" @default.
• W2335020717 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24670858" @default.
• W2335020717 hasPublicationYear "2015" @default.
• W2335020717 type Work @default.
• W2335020717 sameAs 2335020717 @default.
• W2335020717 citedByCount "73" @default.
• W2335020717 countsByYear W23350207172014 @default.
• W2335020717 countsByYear W23350207172015 @default.
• W2335020717 countsByYear W23350207172016 @default.
• W2335020717 countsByYear W23350207172017 @default.
• W2335020717 countsByYear W23350207172018 @default.
• W2335020717 countsByYear W23350207172019 @default.
• W2335020717 countsByYear W23350207172020 @default.
• W2335020717 countsByYear W23350207172021 @default.
• W2335020717 countsByYear W23350207172022 @default.
• W2335020717 countsByYear W23350207172023 @default.
• W2335020717 crossrefType "journal-article" @default.
• W2335020717 hasAuthorship W2335020717A5012229337 @default.
• W2335020717 hasAuthorship W2335020717A5021897609 @default.
• W2335020717 hasAuthorship W2335020717A5028689777 @default.
• W2335020717 hasAuthorship W2335020717A5029774861 @default.
• W2335020717 hasAuthorship W2335020717A5041612225 @default.
• W2335020717 hasAuthorship W2335020717A5062076820 @default.
• W2335020717 hasAuthorship W2335020717A5063900162 @default.
• W2335020717 hasAuthorship W2335020717A5067313142 @default.
• W2335020717 hasAuthorship W2335020717A5073637013 @default.
• W2335020717 hasAuthorship W2335020717A5081036923 @default.
• W2335020717 hasBestOaLocation W23350207172 @default.
• W2335020717 hasConcept C126322002 @default.
• W2335020717 hasConcept C141071460 @default.
• W2335020717 hasConcept C156957248 @default.
• W2335020717 hasConcept C167135981 @default.
• W2335020717 hasConcept C17923572 @default.
• W2335020717 hasConcept C190385971 @default.
• W2335020717 hasConcept C194828623 @default.
• W2335020717 hasConcept C207103383 @default.
• W2335020717 hasConcept C2779936836 @default.
• W2335020717 hasConcept C2780014101 @default.
• W2335020717 hasConcept C2780110798 @default.
• W2335020717 hasConcept C3017944768 @default.
• W2335020717 hasConcept C44249647 @default.
• W2335020717 hasConcept C71924100 @default.
• W2335020717 hasConcept C85004164 @default.
• W2335020717 hasConceptScore W2335020717C126322002 @default.
• W2335020717 hasConceptScore W2335020717C141071460 @default.

• next