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• W2335048034 abstract "Introduction: The altered physiology of burn patients predisposes them to sepsis (up to 20% of patients); however, the complexity of their care often requires prolonged use of CVCs. Methods: Patients were treated in accordance with standard medical practice of the physician and institution. This retrospective review includes data from 155 patients who underwent placement of 455 Spectrum 5-lumen minocycline/rifampin-impregnated CVCs between January 2008 and June 2012. CVCs were placed via Seldinger technique and were changed approximately every 7-10 days, if necessary. CRBSI was defined as at least 1 blood culture (>100,000 colonies) and 1 simultaneous roll-plate CVC tip culture (>15 colony forming units) positive for the same organism. Results: Mean patient age was 49 years and 68% of patients were male. Most patients had accidental burns (82%) with a mean of 50% TBSA affected. Eight patients had sepsis upon admission. The median number of ICU days was 27 days (range 1 to 283 days). The mean number of catheters per patient was 3 (range 1 to 25) and all were placed in the ICU by new percutaneous insertion. US-guidance was used in only 4% of CVC placement procedures. Catheters were inserted in the internal jugular vein (3%), subclavian vein (5%), and femoral vein (91%); 31 catheters (7%) were inserted through burned skin. Mean overall catheter indwell time was 8 days (range 0 to 39 days). There were 3,752 total catheter days. The rate of CRBSI per 1,000 catheter days was 11.2. The most common infectious organism was Acinetobacter baumannii. Eleven patients (7%) experienced DVT. No patient experienced any other catheter-related adverse event (including catheter misplacement, allergy to a catheter antibiotic, arterial puncture, pneumothorax, hemothorax, PE, air embolism, or local infection). One hundred-five patients died; no deaths were attributed to the CVC. Conclusions: The rate of CRBSI was 11.2; this is in accordance with rates of CRBSI in the published literature describing burn patients. Femoral CVC placement did not result in increased CRBSI rates." @default.
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• W2335048034 date "2013-12-01" @default.
• W2335048034 modified "2023-10-18" @default.
• W2335048034 title "818" @default.
• W2335048034 doi "https://doi.org/10.1097/01.ccm.0000440056.69216.d2" @default.
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