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- W2335103696 abstract "Utilizing combinatorial synthesis and a preparative LC-MS automated chromatography system we have prepared and purified a library of 4-[2-(1,2,4-oxadiazolyl)]piperidines that were designed to be novel and selective dopamine D4 ligands. In one round of synthesis we identified N-4-chlorobenzyl-4-[2-(3-(2-thienyl)-1,2, 4-oxadiazolyl)]piperidine with a Kd of 5 nM for the human D4 receptor." @default.
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- W2335103696 date "2000-02-01" @default.
- W2335103696 modified "2023-10-14" @default.
- W2335103696 title "A Solution-Phase Combinatorial Synthesis of Selective Dopamine D4 Ligands" @default.
- W2335103696 doi "https://doi.org/10.2174/1386207003327710" @default.
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