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• W2335179637 abstract "It is now well established that a healthy gut flora is largely responsible for the overall health of the host, while a perturbation in gut microbial communities can contribute to disease susceptibility. Obesity is a complex process involving genetic and environmental factors with an epidemiological burden that makes it a major public health issue. Studies of germ-free or gnotobiotic mice provided evidence that the diversity, as well as the presence and relative proportion of different microbes in the gut play active roles in energy homeostasis. Similarly, human studies showed that both the diversity of the microbiota and the <i>Bacteroidetes/Firmicutes</i> ratio are decreased in obese individuals. The ‘obese microbiota' seems to be able to increase dietary energy harvest and favor weight gain and fat deposition. Although research in this field has just started and many of the available data are still conflicting, the results are providing exciting perspectives, and gut microbiota manipulation has already become a new target for both prevention and treatment of obesity." @default.
• W2335179637 created "2016-06-24" @default.
• W2335179637 creator A5004078668 @default.
• W2335179637 creator A5014595345 @default.
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• W2335179637 creator A5074723888 @default.
• W2335179637 date "2016-01-01" @default.
• W2335179637 modified "2023-10-02" @default.
• W2335179637 title "The Gut Bacteria-Driven Obesity Development" @default.
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• W2335179637 doi "https://doi.org/10.1159/000443356" @default.
• W2335179637 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27028448" @default.
• W2335179637 hasPublicationYear "2016" @default.
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