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- W2335222914 abstract "<h3>Background</h3> Soft tissue sarcomas (STS) in the paediatric age group are relatively uncommon in our environment, with poor documentation in the literature as regards the factors that affect outcome and prognosis. <h3>Aim</h3> To describe the pattern of paediatric STS with emphasis on the grade and stage at the first surgical or medical oncologic intervention. <h3>Methods</h3> Histologically confirmed STS of the Department of Pathology, University College Hospital, Ibadan between January 1991 and December 2010 in children aged 0–14 years were reviewed. <h3>Results</h3> Ninety cases were seen with an almost equal male to female ratio and age range from 5 months to 14 years. The mean age was 7.45 (SD=3.97) years and the peak age group was 5-9 years. Rhabdomyosarcoma was the most common histological type (71.1%). Other types were undifferentiated sarcomas (6.7%), Kaposi sarcoma (5.6%) and 3.3% each for synovial sarcoma, DFSP and fibrosarcoma. The common primary sites were the head and neck (24.1%), orbit (23.0%) and the pelvis (24.1%). 68.8% had histologic grade 3 tumour based on the FNCLCC grading system and 55.6% had stage T2b based on TNM staging. <h3>Conclusion</h3> Majority of our patients present with late stage and high histologic grade tumour thereby conferring poor prognosis at presentation." @default.
- W2335222914 created "2016-06-24" @default.
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- W2335222914 date "2014-01-01" @default.
- W2335222914 modified "2023-09-27" @default.
- W2335222914 title "Paediatric soft tissue sarcomas in a low resource setting: grade and stage at presentation are poor prognostic characteristics" @default.
- W2335222914 doi "https://doi.org/10.1097/01.pat.0000454273.55784.cc" @default.
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