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• W2335263280 abstract "You have accessJournal of UrologyBenign Prostatic Hyperplasia: Epidemiology & Natural History/Evaluation & Markers1 Apr 20131745 IMPACT OF DIABETES MELLITUS ON URINARY SYMPTOM IN MEN WITH LOWER URINARY TRACT SYMPTOMS/BENIGN PROSTATIC HYPERPLASIA: A PROPENSITY SCORE MATCHING STUDY Woo Jin Bang, Joo Yong Lee, Yoon Soo Hah, Dae Hun Lee, Won Sik Ham, and Kang Su Cho Woo Jin BangWoo Jin Bang Anyang, Korea, Republic of More articles by this author , Joo Yong LeeJoo Yong Lee Seoul, Korea, Republic of More articles by this author , Yoon Soo HahYoon Soo Hah Seoul, Korea, Republic of More articles by this author , Dae Hun LeeDae Hun Lee Seoul, Korea, Republic of More articles by this author , Won Sik HamWon Sik Ham Seoul, Korea, Republic of More articles by this author , and Kang Su ChoKang Su Cho Seoul, Korea, Republic of More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2915AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Metabolic syndrome is known to be associated with lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH), and diabetic cystopathy is characterized by impaired sensation of bladder fullness, increased bladder capacity and decreased bladder contractility. However, the impact of controlled diabetes mellitus (DM) on LUTS is still poorly understood. METHODS A prospective database on 905 first-visit patients with LUTS/BPH from April 2010 to June 2012 was used. After excluding those with comorbidities that may affect urinary symptom, 139 patients with DM were selected, and 1 to 1 selected controls were also extracted by propensity scoring matched for age and prostate volume. A total of 278 patients were analyzed, and their mean age was 65.3±9.1 years. RESULTS There were no differences in age, prostate volume, voided volume and maximal flow rate between the two groups, whereas residual urine volume showed a significant difference between patients and controls (29.3±27.0 mL vs. 22.5±23.3, p=0.028). A significant difference of total International Prostatic Symptom Score was noted between patients and controls (17.80±7.60, 15.88±7.05, p=0.031). Patients with DM showed higher storage (7.45±3.21 vs 6.58±3.11, p=0.024) and post-voiding (2.57±1.49 vs. 2.19±1.59, p=0.045) symptom scores compared to controls, whereas no differences were noted in voiding symptom scores (p=0.104). Among storage symptoms, patients with DM showed higher frequency (p=0.010) and nocturia (p=0.003) scores, while there were no differences in urgency scores. Moreover, Overactive Bladder Symptom Score showed significant differences between patients and controls (p=0.006) (Table 1). CONCLUSIONS Diabetic patients with LUTS/BPH showed increased residual urine volume and greater storage and post-micturition symptoms than age/prostate volume-matched controls. This disparity in storage symptoms is thought to arise mainly from frequency and nocturia due to polyuria rather than urgency. Table 1. Difference of urinary symptoms between diabetic and non-diabetic group DM group Non-DM group P-value Number of patients 139 139 - IPSS Total score 17.80±7.60 15.88±7.05 0.031 Voiding symptom 7.90±4.17 7.11±3.84 0.104 Interruption 2.49±1.64 2.14±1.64 0.082 Weak stream 3.21±1.54 3.04±1.50 0.339 Hesitancy 2.20±1.65 1.93±1.56 0.167 Storage symptom 7.45±3.21 6.58±3.11 0.024 Frequency 2.71±1.47 2.27±1.34 0.010 Urgency 2.25±1.45 2.26±1.46 0.951 Nocturia 2.49±1.18 2.06±1.20 0.003 Post-micturition symptom 2.57±1.49 2.19±1.59 0.045 Quality of life 3.88±1.13 3.64±1.13 0.087 OABSS Total score 5.62±3.40 4.54±3.06 0.006 Day-time frequency 0.60±0.56 0.52±0.54 0.240 Nocturia 2.14±0.91 1.71±0.93 Urgency 1.94±1.62 1.60±1.50 0.077 Urge incontinence 0.94±1.47 0.71±1.21 0.155 IPSS: International Prostatic Symptom Score, OABSS: Overactive Bladder Symptom Score © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e717 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Woo Jin Bang Anyang, Korea, Republic of More articles by this author Joo Yong Lee Seoul, Korea, Republic of More articles by this author Yoon Soo Hah Seoul, Korea, Republic of More articles by this author Dae Hun Lee Seoul, Korea, Republic of More articles by this author Won Sik Ham Seoul, Korea, Republic of More articles by this author Kang Su Cho Seoul, Korea, Republic of More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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• W2335263280 title "1745 IMPACT OF DIABETES MELLITUS ON URINARY SYMPTOM IN MEN WITH LOWER URINARY TRACT SYMPTOMS/BENIGN PROSTATIC HYPERPLASIA: A PROPENSITY SCORE MATCHING STUDY" @default.
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