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- W2335294513 abstract "We present a model to describe the response of chip-based nanocavity sensors during extracellular recording of action potentials. These sensors feature microelectrodes which are embedded in liquid-filled cavities. They can be used for the highly localized detection of electrical signals on a chip. We calculate the sensor's impedance and simulate the propagation of action potentials. Subsequently we apply our findings to analyze cell-chip coupling properties. The results are compared to experimental data obtained from cardiomyocyte-like cells. We show that both the impedance and the modeled action potentials fit the experimental data well. Furthermore, we find evidence for a large seal resistance of cardiomyocytes on nanocavity sensors compared to conventional planar recording systems." @default.
- W2335294513 created "2016-06-24" @default.
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- W2335294513 date "2012-03-29" @default.
- W2335294513 modified "2023-09-27" @default.
- W2335294513 title "Frequency-dependent signal transfer at the interface between electrogenic cells and nanocavity electrodes" @default.
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- W2335294513 doi "https://doi.org/10.1103/physreve.85.031917" @default.
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- W2335294513 hasPublicationYear "2012" @default.
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