FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2335468180> ?p ?o ?g. }

• W2335468180 abstract "BACKGROUND: Identifying a hereditary cancer syndrome has the potential to significantly impact a patient9s treatment and long-term management, as well as prevent future malignancies among relatives. Therefore, referral of patients appropriate for genetic counseling and testing is critical. Providers traditionally initiate patient referral; however, this can lead to inconsistent referrals and results in failure to refer more than 50% of appropriate individuals, according to recent studies. In an attempt to address these quality issues, we developed an automatic referral program using the National Comprehensive Cancer Network guidelines, which was approved through our cancer committee and implemented 10/1/10. This pilot was conducted within a genetic counseling program staffed by board certified genetic counselors and associated with a private, multi-disciplinary oncology practice that is part of an American College of Surgeons accredited Network Cancer Center. Our Cancer Center is part of a five-hospital integrated healthcare system and a part of the National Cancer Institute Community Cancer Centers Program network. METHODS: We conducted weekly reviews of oncology patients scheduled for upcoming appointments to identify individuals diagnosed with breast cancer before age 50 or with ovarian, fallopian, or primary peritoneal cancer at any age. Patients previously referred to our genetic counseling program were excluded. Providers were notified weekly of their patients identified via this program, with the option to decline referral. We undertook a retrospective review of the outcomes of individuals identified from 10/1/10 through 10/1/11, with follow up as of 6/1/12. IRB approval was obtained through the University of Louisville. RESULTS: We identified 521 patients for referral, 24 (4.6%) of whom were declined by a provider, resulting in 497 referrals. Three hundred forty one (69%) referrals had breast cancer and 156 (31%) had other malignancies. Of referrals, 139 (28%) have been seen, 223 (45%) have declined, and 135 (27%) are in process. Testing was pursued by 108 (78%) of referrals seen, all of whom had BRCA1/2 testing and 5 (4.6%) of whom had additional testing. We identified 11 (10%) individuals with a BRCA1/2 mutation. An additional 17 (16%) individuals who completed testing were counseled to consider enhanced surveillance in the absence of a confirmed hereditary cancer syndrome. The total number of first degree relatives with potential to benefit from this program is 62 among individuals with a BRCA1/2 mutation and 86 among individuals without a confirmed hereditary cancer syndrome. CONCLUSIONS: Initiation of an automatic genetic counseling referral program in the setting of a large oncology practice is feasible and has the potential to identify individuals with a BRCA1/2 mutation who might otherwise go undetected. Few providers object to referral, and the majority of patients are receptive to referral. The impact of this program extends beyond those identified with a BRCA1/2 mutation. This project was funded in part with federal funds: NCI, NIH Contract No. HHSN261200800001E. Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P4-11-06." @default.
• W2335468180 created "2016-06-24" @default.
• W2335468180 creator A5028466810 @default.
• W2335468180 creator A5051007846 @default.
• W2335468180 creator A5060210684 @default.
• W2335468180 creator A5075469241 @default.
• W2335468180 creator A5087196493 @default.
• W2335468180 date "2012-12-15" @default.
• W2335468180 modified "2023-09-27" @default.
• W2335468180 title "Abstract P4-11-06: Automatic referral to genetic counseling for identification ofBRCA1/2mutations: a pilot program at Norton Cancer Institute, Louisville, KY." @default.
• W2335468180 doi "https://doi.org/10.1158/0008-5472.sabcs12-p4-11-06" @default.
• W2335468180 hasPublicationYear "2012" @default.
• W2335468180 type Work @default.
• W2335468180 sameAs 2335468180 @default.
• W2335468180 citedByCount "1" @default.
• W2335468180 countsByYear W23354681802015 @default.
• W2335468180 crossrefType "proceedings-article" @default.
• W2335468180 hasAuthorship W2335468180A5028466810 @default.
• W2335468180 hasAuthorship W2335468180A5051007846 @default.
• W2335468180 hasAuthorship W2335468180A5060210684 @default.
• W2335468180 hasAuthorship W2335468180A5075469241 @default.
• W2335468180 hasAuthorship W2335468180A5087196493 @default.
• W2335468180 hasConcept C121608353 @default.
• W2335468180 hasConcept C126322002 @default.
• W2335468180 hasConcept C2776135927 @default.
• W2335468180 hasConcept C2776559941 @default.
• W2335468180 hasConcept C2780673598 @default.
• W2335468180 hasConcept C509550671 @default.
• W2335468180 hasConcept C512399662 @default.
• W2335468180 hasConcept C526805850 @default.
• W2335468180 hasConcept C54355233 @default.
• W2335468180 hasConcept C60748783 @default.
• W2335468180 hasConcept C61521584 @default.
• W2335468180 hasConcept C71924100 @default.
• W2335468180 hasConcept C80227256 @default.
• W2335468180 hasConcept C86803240 @default.
• W2335468180 hasConceptScore W2335468180C121608353 @default.
• W2335468180 hasConceptScore W2335468180C126322002 @default.
• W2335468180 hasConceptScore W2335468180C2776135927 @default.
• W2335468180 hasConceptScore W2335468180C2776559941 @default.
• W2335468180 hasConceptScore W2335468180C2780673598 @default.
• W2335468180 hasConceptScore W2335468180C509550671 @default.
• W2335468180 hasConceptScore W2335468180C512399662 @default.
• W2335468180 hasConceptScore W2335468180C526805850 @default.
• W2335468180 hasConceptScore W2335468180C54355233 @default.
• W2335468180 hasConceptScore W2335468180C60748783 @default.
• W2335468180 hasConceptScore W2335468180C61521584 @default.
• W2335468180 hasConceptScore W2335468180C71924100 @default.
• W2335468180 hasConceptScore W2335468180C80227256 @default.
• W2335468180 hasConceptScore W2335468180C86803240 @default.
• W2335468180 hasLocation W23354681801 @default.
• W2335468180 hasOpenAccess W2335468180 @default.
• W2335468180 hasPrimaryLocation W23354681801 @default.
• W2335468180 hasRelatedWork W1974705032 @default.
• W2335468180 hasRelatedWork W1988869503 @default.
• W2335468180 hasRelatedWork W2013541564 @default.
• W2335468180 hasRelatedWork W2050676728 @default.
• W2335468180 hasRelatedWork W2089207678 @default.
• W2335468180 hasRelatedWork W2130349899 @default.
• W2335468180 hasRelatedWork W2162899562 @default.
• W2335468180 hasRelatedWork W2165227514 @default.
• W2335468180 hasRelatedWork W2286002509 @default.
• W2335468180 hasRelatedWork W2341470967 @default.
• W2335468180 hasRelatedWork W2590134354 @default.
• W2335468180 hasRelatedWork W2744030789 @default.
• W2335468180 hasRelatedWork W2795192541 @default.
• W2335468180 hasRelatedWork W2800129371 @default.
• W2335468180 hasRelatedWork W2900899591 @default.
• W2335468180 hasRelatedWork W3098779664 @default.
• W2335468180 hasRelatedWork W3138427114 @default.
• W2335468180 hasRelatedWork W3204264837 @default.
• W2335468180 hasRelatedWork W71252127 @default.
• W2335468180 hasRelatedWork W2120859893 @default.
• W2335468180 isParatext "false" @default.
• W2335468180 isRetracted "false" @default.
• W2335468180 magId "2335468180" @default.
• W2335468180 workType "article" @default.