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- W2335531961 abstract "The question of structural and functional recovery of central nervous system tissue in mammals is still a moot point. There are many experiments dealing with regeneration of the optic nerve in fish but practically none in higher forms. Sugar and Gerard studied regeneration of the spinal cord in the rat and found that “true anatomical and physiological regeneration can occur in the rat spinal cord.” We studied the recovery of the pupillary light reflex after sectioning the optic nerves in 3 cats and 4 monkeys by the pupillographic method as developed by Lowenstein. The recordings were made in the dark with infra-red sensitive film. The film was then projected on a screen and pupillary diameter measurements made in tenths of mm. The time intervals were in tenths and seconds. From 16 to 17 months after the (right) optic and ciliary nerves were severed just behind the globe, direct (of the operated eye) and consensual (of the normal eye) constriction was found when a light of 60 watts at a distance of 1 meter was projected on the experimental (right) eye. Great care was taken to insure that no amount of light would reach the normal (left) eye. In several experiments a heavy bandage was placed on the normal eye; in the other cases where the consensual reaction of the other eye was to be recorded, this eye was carefully protected against direct stimulation. The direct pupillary response was found to be minimal-achange from 0.1 to 0.5 mm. The consensual response, i. e., from the experimental eye to the normal eye was slightly more conspicuous, showing constriction of 0.5 to 1.5 mm, while the consensual reaction from the normal to the operated eye manifested by a decrease of 2.0 to 3.0 mm in the pupillary diameter." @default.
- W2335531961 created "2016-06-24" @default.
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- W2335531961 date "1941-11-01" @default.
- W2335531961 modified "2023-09-23" @default.
- W2335531961 title "Recovery of Pupillary Function in Cut Optic Nerves of Cats and Monkeys." @default.
- W2335531961 doi "https://doi.org/10.3181/00379727-48-13351p" @default.
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