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- W2335584557 abstract "Mass spectrometry (MS)-based proteomics assays provide unprecedented opportunities for determination of protein expression in tissues for clinical applications. Within the last few years a number of clinical assays have been established. These include multiplexed selected reaction monitoring based approaches to quantify protein targets of therapeutic agents in cancer tissues and bottom-up shotgun MS-based proteomics approaches to diagnose and classify protein deposition disorders such as amyloidosis. These examples highlight the vast potential of MS-based proteomics as analytical and descriptive tools for clinical diagnosis of human disease. However, a number of major challenges remain for broader application and acceptance of such technologies in routine clinical care." @default.
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- W2335584557 date "2014-09-04" @default.
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- W2335584557 title "Advances in clinical applications of tissue proteomics: opportunities and challenges" @default.
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- W2335584557 doi "https://doi.org/10.1586/14789450.2014.953062" @default.
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