Matches in SemOpenAlex for { <https://semopenalex.org/work/W2335703089> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2335703089 endingPage "150" @default.
- W2335703089 startingPage "146" @default.
- W2335703089 abstract "Stromelysin 3 (ST3) is a member of the metalloproteinase family, which is expressed in the skin during wound healing and in the stroma of basal cell carcinoma. A high level of expression of ST3 has been observed in carcinomas of poor prognosis. In benign tumors, though, ST3 is not expressed or is at a low level. We have immunohistochemically studied the expression of ST3 in 89 randomly selected cases of squamous cell carcinomas (SCCs), 104 of keratoacanthomas (KA), and 23 cases of metastatic SCC. Stromelysin 3 was expressed only by fibroblasts surrounding the tumors and not by epithelial cells. The proportion of tumors positively stained was 22% of KA, 47% of randomly selected SCC, and 70% of metastatic SCC. In areas of poorly demarcated neoplastic cells, a reinforcement of the staining was observed in the stroma. The intensity and dispersion of staining were used to determine the level of expression. There were significantly more SCC in the groups of high expression levels, and both parameters were significantly higher in SCC than in KA. Expression of ST3 in benign tumors is unusual. Its expression in the the stroma of keratoacanthomas can be related to the high tissue remodeling activity observed in these tumors. It also could be interpreted as in favor of the neoplastic nature of KA. Nevertheless, the level of expression was higher in SCC than in KA and seemed to be related to the prognosis of these tumors. These results correlate well with those obtained in breast cancers and in noncutaneous SCC." @default.
- W2335703089 created "2016-06-24" @default.
- W2335703089 creator A5015793986 @default.
- W2335703089 creator A5032032601 @default.
- W2335703089 creator A5040301282 @default.
- W2335703089 creator A5048575128 @default.
- W2335703089 creator A5069428632 @default.
- W2335703089 creator A5090553121 @default.
- W2335703089 date "1999-04-01" @default.
- W2335703089 modified "2023-10-11" @default.
- W2335703089 title "Expression of Stromelysin 3 in Keratoacanthoma and Squamous Cell Carcinoma" @default.
- W2335703089 cites W1894541755 @default.
- W2335703089 cites W1942960670 @default.
- W2335703089 cites W1974203538 @default.
- W2335703089 cites W1992579203 @default.
- W2335703089 cites W2014690489 @default.
- W2335703089 cites W2032877238 @default.
- W2335703089 cites W2036328142 @default.
- W2335703089 cites W2043254359 @default.
- W2335703089 cites W2052626837 @default.
- W2335703089 cites W2072438573 @default.
- W2335703089 cites W2073484019 @default.
- W2335703089 cites W2077255115 @default.
- W2335703089 cites W2088372765 @default.
- W2335703089 cites W2095498651 @default.
- W2335703089 cites W2109658199 @default.
- W2335703089 cites W2131212786 @default.
- W2335703089 cites W2134976853 @default.
- W2335703089 cites W2138964992 @default.
- W2335703089 cites W2335527712 @default.
- W2335703089 doi "https://doi.org/10.1097/00000372-199904000-00006" @default.
- W2335703089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10218674" @default.
- W2335703089 hasPublicationYear "1999" @default.
- W2335703089 type Work @default.
- W2335703089 sameAs 2335703089 @default.
- W2335703089 citedByCount "30" @default.
- W2335703089 countsByYear W23357030892012 @default.
- W2335703089 countsByYear W23357030892013 @default.
- W2335703089 countsByYear W23357030892015 @default.
- W2335703089 countsByYear W23357030892016 @default.
- W2335703089 countsByYear W23357030892017 @default.
- W2335703089 crossrefType "journal-article" @default.
- W2335703089 hasAuthorship W2335703089A5015793986 @default.
- W2335703089 hasAuthorship W2335703089A5032032601 @default.
- W2335703089 hasAuthorship W2335703089A5040301282 @default.
- W2335703089 hasAuthorship W2335703089A5048575128 @default.
- W2335703089 hasAuthorship W2335703089A5069428632 @default.
- W2335703089 hasAuthorship W2335703089A5090553121 @default.
- W2335703089 hasConcept C142724271 @default.
- W2335703089 hasConcept C1491633281 @default.
- W2335703089 hasConcept C16930146 @default.
- W2335703089 hasConcept C204232928 @default.
- W2335703089 hasConcept C2777546739 @default.
- W2335703089 hasConcept C2778804307 @default.
- W2335703089 hasConcept C2779049991 @default.
- W2335703089 hasConcept C2994460389 @default.
- W2335703089 hasConcept C3019992690 @default.
- W2335703089 hasConcept C52124034 @default.
- W2335703089 hasConcept C54355233 @default.
- W2335703089 hasConcept C71924100 @default.
- W2335703089 hasConcept C74864618 @default.
- W2335703089 hasConcept C86803240 @default.
- W2335703089 hasConceptScore W2335703089C142724271 @default.
- W2335703089 hasConceptScore W2335703089C1491633281 @default.
- W2335703089 hasConceptScore W2335703089C16930146 @default.
- W2335703089 hasConceptScore W2335703089C204232928 @default.
- W2335703089 hasConceptScore W2335703089C2777546739 @default.
- W2335703089 hasConceptScore W2335703089C2778804307 @default.
- W2335703089 hasConceptScore W2335703089C2779049991 @default.
- W2335703089 hasConceptScore W2335703089C2994460389 @default.
- W2335703089 hasConceptScore W2335703089C3019992690 @default.
- W2335703089 hasConceptScore W2335703089C52124034 @default.
- W2335703089 hasConceptScore W2335703089C54355233 @default.
- W2335703089 hasConceptScore W2335703089C71924100 @default.
- W2335703089 hasConceptScore W2335703089C74864618 @default.
- W2335703089 hasConceptScore W2335703089C86803240 @default.
- W2335703089 hasIssue "2" @default.
- W2335703089 hasLocation W23357030891 @default.
- W2335703089 hasLocation W23357030892 @default.
- W2335703089 hasOpenAccess W2335703089 @default.
- W2335703089 hasPrimaryLocation W23357030891 @default.
- W2335703089 hasRelatedWork W1505286444 @default.
- W2335703089 hasRelatedWork W1990880506 @default.
- W2335703089 hasRelatedWork W1996311456 @default.
- W2335703089 hasRelatedWork W2075514436 @default.
- W2335703089 hasRelatedWork W2362690455 @default.
- W2335703089 hasRelatedWork W24406720 @default.
- W2335703089 hasRelatedWork W2616815604 @default.
- W2335703089 hasRelatedWork W2747841794 @default.
- W2335703089 hasRelatedWork W4234020564 @default.
- W2335703089 hasRelatedWork W4235520607 @default.
- W2335703089 hasVolume "21" @default.
- W2335703089 isParatext "false" @default.
- W2335703089 isRetracted "false" @default.
- W2335703089 magId "2335703089" @default.
- W2335703089 workType "article" @default.