FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2335713961> ?p ?o ?g. }

• W2335713961 endingPage "693" @default.
• W2335713961 startingPage "685" @default.
• W2335713961 abstract "Optimal dosing strategies have not been established for rabbit antithymocyte globulin (rATG) after heart transplantation, and there is currently wide variability in rATG regimens with respect to both dose and duration.In a retrospective, single-center analysis, 523 patients undergoing heart transplantation during 1996 to 2009 were stratified by cumulative rATG dose: less than 4.5 mg/kg (group A), 4.5 to 7.5 mg/kg (group B) or greater than 7.5 mg/kg (group C).Survival at 1 year after transplantation was 80% in group A, 90% in group B, and 88% in group C (P = 0.062). Incidence of acute rejection per 1000 patient-years was significantly higher in group A (hazards ratio [HR], 54.8; 95% confidence interval [95% CI], 33.9-83.8) compared to groups B (19.6; 95% CI, 11.4-31.4) and C (23.6; 95% CI, 17.5-31.3). Incidence of severe infection 10 years after transplantation was higher in group C (45%) than groups A (37%) or B (23%) (P < 0.001); cytomegalovirus infection rates were 35%, 20% and 23%, respectively (P = 0.009). Multivariable Cox regression showed an HR of 0.51 (95% CI, 0.25-1.02) for acute rejection with group B versus group A, and 0.54 (95% CI, 0.33-0.88; P = 0.013) for severe infection. The rate of malignancy per 1000 patient-years was higher in groups B (13.85) and C (14.95) than group A (7.83).These retrospective data suggest that a cumulative rATG dose of 4.5 to 7.5 mg/kg may offer a better risk-benefit ratio than lower or higher doses, with acceptable rates of infection and posttransplant malignancy. Prospective trials are needed." @default.
• W2335713961 created "2016-06-24" @default.
• W2335713961 creator A5007086755 @default.
• W2335713961 creator A5036203401 @default.
• W2335713961 creator A5036557921 @default.
• W2335713961 creator A5039364058 @default.
• W2335713961 creator A5043459439 @default.
• W2335713961 creator A5048784657 @default.
• W2335713961 creator A5061906956 @default.
• W2335713961 creator A5074376967 @default.
• W2335713961 creator A5075517410 @default.
• W2335713961 creator A5077425012 @default.
• W2335713961 creator A5089983993 @default.
• W2335713961 date "2016-03-01" @default.
• W2335713961 modified "2023-10-07" @default.
• W2335713961 title "Impact of Rabbit Antithymocyte Globulin Dose on Long-term Outcomes in Heart Transplant Patients" @default.
• W2335713961 cites W1976474080 @default.
• W2335713961 cites W1977703774 @default.
• W2335713961 cites W1979589362 @default.
• W2335713961 cites W1992704984 @default.
• W2335713961 cites W1992967149 @default.
• W2335713961 cites W1995073129 @default.
• W2335713961 cites W1997921040 @default.
• W2335713961 cites W2008931717 @default.
• W2335713961 cites W2014752904 @default.
• W2335713961 cites W2015878807 @default.
• W2335713961 cites W2027447956 @default.
• W2335713961 cites W2057431164 @default.
• W2335713961 cites W2061649963 @default.
• W2335713961 cites W2072681900 @default.
• W2335713961 cites W2079830501 @default.
• W2335713961 cites W2091851863 @default.
• W2335713961 cites W2103383683 @default.
• W2335713961 cites W2104575249 @default.
• W2335713961 cites W2105086997 @default.
• W2335713961 cites W2110621091 @default.
• W2335713961 cites W2110758097 @default.
• W2335713961 cites W2127031582 @default.
• W2335713961 cites W2132220648 @default.
• W2335713961 cites W2144232839 @default.
• W2335713961 cites W2171193454 @default.
• W2335713961 cites W2314905526 @default.
• W2335713961 doi "https://doi.org/10.1097/tp.0000000000000950" @default.
• W2335713961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26457604" @default.
• W2335713961 hasPublicationYear "2016" @default.
• W2335713961 type Work @default.
• W2335713961 sameAs 2335713961 @default.
• W2335713961 citedByCount "12" @default.
• W2335713961 countsByYear W23357139612016 @default.
• W2335713961 countsByYear W23357139612017 @default.
• W2335713961 countsByYear W23357139612018 @default.
• W2335713961 countsByYear W23357139612020 @default.
• W2335713961 countsByYear W23357139612021 @default.
• W2335713961 countsByYear W23357139612022 @default.
• W2335713961 crossrefType "journal-article" @default.
• W2335713961 hasAuthorship W2335713961A5007086755 @default.
• W2335713961 hasAuthorship W2335713961A5036203401 @default.
• W2335713961 hasAuthorship W2335713961A5036557921 @default.
• W2335713961 hasAuthorship W2335713961A5039364058 @default.
• W2335713961 hasAuthorship W2335713961A5043459439 @default.
• W2335713961 hasAuthorship W2335713961A5048784657 @default.
• W2335713961 hasAuthorship W2335713961A5061906956 @default.
• W2335713961 hasAuthorship W2335713961A5074376967 @default.
• W2335713961 hasAuthorship W2335713961A5075517410 @default.
• W2335713961 hasAuthorship W2335713961A5077425012 @default.
• W2335713961 hasAuthorship W2335713961A5089983993 @default.
• W2335713961 hasConcept C120665830 @default.
• W2335713961 hasConcept C121332964 @default.
• W2335713961 hasConcept C126322002 @default.
• W2335713961 hasConcept C141071460 @default.
• W2335713961 hasConcept C167135981 @default.
• W2335713961 hasConcept C207103383 @default.
• W2335713961 hasConcept C2777288759 @default.
• W2335713961 hasConcept C2777785397 @default.
• W2335713961 hasConcept C2778849806 @default.
• W2335713961 hasConcept C2780073493 @default.
• W2335713961 hasConcept C2780678043 @default.
• W2335713961 hasConcept C2911091166 @default.
• W2335713961 hasConcept C44249647 @default.
• W2335713961 hasConcept C50382708 @default.
• W2335713961 hasConcept C61511704 @default.
• W2335713961 hasConcept C71924100 @default.
• W2335713961 hasConcept C81358767 @default.
• W2335713961 hasConcept C88879693 @default.
• W2335713961 hasConcept C90924648 @default.
• W2335713961 hasConceptScore W2335713961C120665830 @default.
• W2335713961 hasConceptScore W2335713961C121332964 @default.
• W2335713961 hasConceptScore W2335713961C126322002 @default.
• W2335713961 hasConceptScore W2335713961C141071460 @default.
• W2335713961 hasConceptScore W2335713961C167135981 @default.
• W2335713961 hasConceptScore W2335713961C207103383 @default.
• W2335713961 hasConceptScore W2335713961C2777288759 @default.
• W2335713961 hasConceptScore W2335713961C2777785397 @default.
• W2335713961 hasConceptScore W2335713961C2778849806 @default.
• W2335713961 hasConceptScore W2335713961C2780073493 @default.
• W2335713961 hasConceptScore W2335713961C2780678043 @default.
• W2335713961 hasConceptScore W2335713961C2911091166 @default.
• W2335713961 hasConceptScore W2335713961C44249647 @default.

• next