FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2335726166> ?p ?o ?g. }

• W2335726166 endingPage "71" @default.
• W2335726166 startingPage "65" @default.
• W2335726166 abstract "Background Immunoassays are susceptible to analytical interferences including from endogenous immunoglobulin antibodies at a rate of ∼0.4% to 4%. Hundreds of millions of immunoassay tests (>10 millions in the UK alone) are performed yearly worldwide for measurements of an array of large and small moieties such as proteins, hormones, tumour markers, rheumatoid factor, troponin, small peptides, steroids and drugs. Methods Interference in these tests can lead to false results which when suspected, or surmised, can be analytically confirmed in most cases. Suspecting false laboratory data in the first place is not difficult when results are gross and without clinical correlates. However, when false results are subtle and/or plausible, it can be difficult to suspect with adverse clinical sequelae. This problem can be ameliorated by using a probabilistic Bayesian reasoning to flag up potentially suspect results even when laboratory data appear “not-unreasonable”. Results Essentially, in disorders with low prevalence, the majority of positive results caused by analytical interference are likely to be false positives. On the other hand, when the disease prevalence is high, false negative results increase and become more significant. To illustrate the scope and utility of this approach, six different examples covering wide range of analytes are given, each highlighting specific aspect/nature of interference and suggested options to reduce it. Conclusion Bayesian reasoning would allow laboratorians and/or clinicians to extract information about potentially false results, thus seeking follow-up confirmatory tests prior to the initiation of more expensive/invasive procedures or concluding a potentially wrong diagnosis." @default.
• W2335726166 created "2016-06-24" @default.
• W2335726166 creator A5038189742 @default.
• W2335726166 creator A5078954385 @default.
• W2335726166 creator A5089983488 @default.
• W2335726166 date "2010-11-23" @default.
• W2335726166 modified "2023-09-28" @default.
• W2335726166 title "Probabilistic Bayesian reasoning can help identifying potentially wrong immunoassays results in clinical practice: even when they appear ‘not-unreasonable’" @default.
• W2335726166 cites W1501144897 @default.
• W2335726166 cites W1877026825 @default.
• W2335726166 cites W1895546553 @default.
• W2335726166 cites W1925315080 @default.
• W2335726166 cites W1963787406 @default.
• W2335726166 cites W1965074787 @default.
• W2335726166 cites W1967595093 @default.
• W2335726166 cites W1968927422 @default.
• W2335726166 cites W1973048745 @default.
• W2335726166 cites W1977945712 @default.
• W2335726166 cites W1978172513 @default.
• W2335726166 cites W1981465686 @default.
• W2335726166 cites W1983719065 @default.
• W2335726166 cites W1983904122 @default.
• W2335726166 cites W1999676122 @default.
• W2335726166 cites W2000558679 @default.
• W2335726166 cites W2014788965 @default.
• W2335726166 cites W2015811019 @default.
• W2335726166 cites W2015856716 @default.
• W2335726166 cites W2017892428 @default.
• W2335726166 cites W2017987083 @default.
• W2335726166 cites W2019730500 @default.
• W2335726166 cites W2021821322 @default.
• W2335726166 cites W2022685000 @default.
• W2335726166 cites W2029936373 @default.
• W2335726166 cites W2033276548 @default.
• W2335726166 cites W2040904070 @default.
• W2335726166 cites W2046260402 @default.
• W2335726166 cites W2056226832 @default.
• W2335726166 cites W2065685721 @default.
• W2335726166 cites W2068195813 @default.
• W2335726166 cites W2079100169 @default.
• W2335726166 cites W2080915632 @default.
• W2335726166 cites W2082568215 @default.
• W2335726166 cites W2087954063 @default.
• W2335726166 cites W2095761465 @default.
• W2335726166 cites W2096400482 @default.
• W2335726166 cites W2109986594 @default.
• W2335726166 cites W2110369052 @default.
• W2335726166 cites W2120779783 @default.
• W2335726166 cites W2123802026 @default.
• W2335726166 cites W2124365160 @default.
• W2335726166 cites W2132182315 @default.
• W2335726166 cites W2135137476 @default.
• W2335726166 cites W2136788998 @default.
• W2335726166 cites W2152464791 @default.
• W2335726166 cites W2166251806 @default.
• W2335726166 cites W2166290486 @default.
• W2335726166 cites W2167184544 @default.
• W2335726166 cites W2168015482 @default.
• W2335726166 cites W2168794783 @default.
• W2335726166 cites W2169735148 @default.
• W2335726166 cites W2238369005 @default.
• W2335726166 cites W2317833825 @default.
• W2335726166 cites W2413773352 @default.
• W2335726166 cites W2026697673 @default.
• W2335726166 doi "https://doi.org/10.1258/acb.2010.010197" @default.
• W2335726166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21098546" @default.
• W2335726166 hasPublicationYear "2010" @default.
• W2335726166 type Work @default.
• W2335726166 sameAs 2335726166 @default.
• W2335726166 citedByCount "13" @default.
• W2335726166 countsByYear W23357261662012 @default.
• W2335726166 countsByYear W23357261662013 @default.
• W2335726166 countsByYear W23357261662014 @default.
• W2335726166 countsByYear W23357261662016 @default.
• W2335726166 countsByYear W23357261662017 @default.
• W2335726166 countsByYear W23357261662019 @default.
• W2335726166 crossrefType "journal-article" @default.
• W2335726166 hasAuthorship W2335726166A5038189742 @default.
• W2335726166 hasAuthorship W2335726166A5078954385 @default.
• W2335726166 hasAuthorship W2335726166A5089983488 @default.
• W2335726166 hasConcept C107673813 @default.
• W2335726166 hasConcept C112789634 @default.
• W2335726166 hasConcept C119857082 @default.
• W2335726166 hasConcept C149782125 @default.
• W2335726166 hasConcept C154945302 @default.
• W2335726166 hasConcept C15744967 @default.
• W2335726166 hasConcept C2778223634 @default.
• W2335726166 hasConcept C33923547 @default.
• W2335726166 hasConcept C41008148 @default.
• W2335726166 hasConcept C49937458 @default.
• W2335726166 hasConcept C64869954 @default.
• W2335726166 hasConcept C71924100 @default.
• W2335726166 hasConcept C73484699 @default.
• W2335726166 hasConcept C95922358 @default.
• W2335726166 hasConceptScore W2335726166C107673813 @default.
• W2335726166 hasConceptScore W2335726166C112789634 @default.
• W2335726166 hasConceptScore W2335726166C119857082 @default.
• W2335726166 hasConceptScore W2335726166C149782125 @default.

• next