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- W2335742816 endingPage "445" @default.
- W2335742816 startingPage "436" @default.
- W2335742816 abstract "Hemophagocytic syndrome is a severe and often fatal syndrome resulting from excessive activation and proliferation of T lymphocytes and macrophages. Onset of a hemophagocytic syndrome characterized the course of several human inherited immune disorders, all of them resulting from molecular defects of the perforin-dependent cytotoxic process exerted by both T and Natural Killer (NK) lymphocytes. These disorders highlight the determinant role of this lytic pathway in the control of lymphocyte expansion and homeostasis. New effectors of this secretory pathway have been thus identified." @default.
- W2335742816 created "2016-06-24" @default.
- W2335742816 creator A5029004287 @default.
- W2335742816 creator A5047506862 @default.
- W2335742816 date "2003-07-01" @default.
- W2335742816 modified "2023-10-03" @default.
- W2335742816 title "Defective cytotoxic granule-mediated cell death pathway impairs T lymphocyte homeostasis" @default.
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- W2335742816 doi "https://doi.org/10.1097/00002281-200307000-00011" @default.
- W2335742816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12819472" @default.
- W2335742816 hasPublicationYear "2003" @default.
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