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• W2335914450 abstract "The greatest challenge when working with mathematical models describing biological processes is to choose appropriate values of kinetic parameters. This applies especially to the models of environmental biological processes, such as bioremediation. Parameter values are usually obtained from various sources and under specific experimental conditions and constitute sources of uncertainties. A useful tool for dealing with model parameter uncertainties is sensitivity analysis. It studies how a given model depends on its input factors. In this work, the nonstationary Extended Fourier Amplitude Sensitivity analysis was used to analyze the effect of 28 kinetic parameters on 18 metabolite concentrations and 16 reaction rates of the biological part of the integrated BTEX bioremediation model. First-order sensitivities and total effect indices were estimated for three time points of the process to identify the places of the metabolism control shift. Analyses revealed that the model is nonadditive and there are no strong interactions between the parameters. Results of this study indicate the importance of using the global sensitivity analysis before bioremediation process planning." @default.
• W2335914450 created "2016-06-24" @default.
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• W2335914450 date "2016-06-01" @default.
• W2335914450 modified "2023-10-18" @default.
• W2335914450 title "Global Sensitivity Analysis of the Biological Part of the Integrated BTEX Bioremediation Model" @default.
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• W2335914450 doi "https://doi.org/10.1089/ees.2015.0325" @default.
• W2335914450 hasPublicationYear "2016" @default.
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